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Acute Ischemic Stroke
This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
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The Childhood of Jesus
This is an extraordinary new fable from one of the world's greatest living novelists, two-time Booker Prize winner and Nobel Laureate. David is a small boy who comes by boat across the ocean to a new country. He has been separated from his parents, and has lost the piece of paper that would have explained everything. On the boat a stranger named Simon takes it upon himself to look after the boy. On arrival they are assigned new names, new birthdates. They know little Spanish, the language of their new country, and nothing about its customs. They have also suffered a kind of forgetting of old attachments and feelings. They are people without a past. Simon's goal is to find the boy's mother. H...
White Noise
The Gladney's family life is disrupted and threatened when an industrial accident sends a lethal cloud over their community. Jack Gladney struggles with the ensuing complications which include murder.
Molecular Pathology of Breast Cancer
The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next gener...
Why Be Happy When You Could Be Normal?
A New York Times bestseller: The “magnificent” memoir by one of the bravest and most original writers of our time—“A tour de force of literature and love” (Vogue). One of the New York Times’ “50 Best Memoirs of the Past 50 Years” Jeanette Winterson’s bold and revelatory novels have established her as a major figure in world literature. Her internationally best-selling debut, Oranges Are Not the Only Fruit, tells the story of a young girl adopted by Pentecostal parents, and has become a staple of required reading in contemporary fiction classes. Why Be Happy When You Could Be Normal? is a “singular and electric” memoir about a life’s work to find happiness (The New Yor...
'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine
This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.
I'll Go to Bed at Noon
Colette Jones has had drink problems in the past, but now it seems as though her whole family is in danger of turning to alcohol. Her oldest son has thrown away a promising musical career for a job behind the counter in a builders' merchants, and his drinking sprees with his brother-in-law Bill, a pseudo-Marxist supermarket butcher who seems to see alcohol as central to the proletarian revolution, have started to land him in trouble with the police. Meanwhile Colette's recently widowered older brother is following an equally self-destructive path, having knocked back an entire cellar of homemade wine, he's now on the gin, a bottle a day and counting. Who will be next? Her youngest son had de...
Current Organic Chemistry
Provides in depth reviews on current progress in the fields of asymmetric synthesis, organometallic chemistry, bioorganic chemistry, heterocyclic chemistry, natural product chemistry, and analytical methods in organic chemistry. Each issue is edited by an appointed Executive Guest Editor
Protein Tyrosine Phosphatases in Cancer
This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features of the PTP superfamily, including their overall structure and enzymological properties; use selected examples of individual PTP superfamily members, to illustrate emerging data on the role of PTPs in cancer; and will review the current status of PTP-based drug development efforts. Protein Tyrosine Phosphatases in Cancer,from renowned researchers Benjamin Neel and Nicholas Tonks, is invaluable reading for researchers in oncology, stem cell signaling,and biochemistry.
