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Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis.
Sarcoidosis is a type of inflammation that occurs in various locations of the body for no known reason. Normally, when foreign substances or organisms enter the body, the immune system will fight back by activating an immune response. Inflammation is a normal part of this immune response, but it should subside once the foreign antigen is gone. In sarcoidosis, the inflammation persists, and some of the immune cells form abnormal clumps of tissue called granulomas. The disease can affect any organ in the body, but it is most likely to occur in the lungs. It can also affect the skin, eyes, liver, or lymph nodes. Although the cause of sarcoidosis is not known, research suggests that it may be du...
The scope of OMF surgery has expanded; encompassing treatment of diseases, disorders, defects and injuries of the head, face, jaws and oral cavity. This internationally-recognized specialty is evolving with advancements in technology and instrumentation. Specialists of this discipline treat patients with impacted teeth, facial pain, misaligned jaws, facial trauma, oral cancer, cysts and tumors; they also perform facial cosmetic surgery and place dental implants. The contents of this volume essentially complements the volume 1; with chapters that cover both basic and advanced concepts on complex topics in oral and maxillofacial surgery.
Physical attractiveness of the face has a significant impact on the social life and daily interaction of individuals as well as one’s general perception of life. Proper surgical planning for aesthetic facial surgery requires a meticulous analysis of the patient’s current and desired facial features from the perspective of both soft and hard tissues. Significantly greater changes to facial aesthetics can be made via the alteration of the main bony structures of the face than by alteration of soft tissue and skin alone. Various surgical and clinical techniques are available for the augmentation, reduction or refinement of the most prominent aspects of facial aesthetics, such as alterations...
Focusing on the anatomy of the head and neck, this book begins at the cellular level of development, detailing bone, muscle, blood supply, and innervation along the way. It illustrates the origin of each tissue structure to aid in making prognoses beyond the surface deformation, offering typical issues seen in the craniofacial region, for example. Written by a pediatric Craniofacial plastic surgeon and intended for clinicians and residents in the areas of plastic surgery, ENT, maxillofacial surgery, and orthodontistry, this book is the first of its kind to focus so intently on evolution of the craniofacial structure. It is neatly broken up into two distinct sections. The first section is mea...
The book Biomaterials in Regenerative Medicine is addressed to the engineers and mainly medical practitioners as well as scientists and PhD degree students. The book indicates the progress in research and in the implementation of the ever-new biomaterials for the application of the advanced types of prosthesis, implants, scaffolds and implant-scaffolds including personalised ones. The book presents a theoretical approach to the synergy of technical, biological and medical sciences concerning materials and technologies used for medical and dental implantable devices and on metallic biomaterials. The essential contents of the book are 16 case studies provided in each of the chapters, comprehensively describing the authors' accomplishments of numerous teams from different countries across the world in advanced research areas relating to the biomaterials applied in regenerative medicine and dentistry. The detailed information collected in the book, mainly deriving from own and original research and R
Advanced oral and maxillofacial surgery encompasses a vast array of diseases, disorders, defects, and deformities as well as injuries of the mouth, head, face, and jaws. It relates not only to treatment of impacted teeth, facial pain, misaligned jaws, facial trauma, oral cancers, jaw cysts, and tumors but also to facial cosmetic surgery and placement of dental and facial implants. This specialty is evolving alongside advancements in technology and instrumentation. Volume 1 has topped 132,000 chapter downloads so far, and Volume 2 is being downloaded at the same pace! Volume 3 is basically the sequel to Volumes 1 and 2; 93 specialists from nine countries contributed to 32 chapters providing comprehensive coverage of advanced topics in OMF surgery.
Cone Beam Computed Tomography is one of the new 3D imaging technologies used to identify the proximity of the inferior alveolar nerve to the impacted Mandibular third molar. Although Orthopantomogram has been used for a long period, CBCT is still considered a Gold Standard for planning the surgery and preventing nerve injury during Mandibular third molar surgery
The aim of this book is to present the latest applications, trends, and developments of computer-aided technologies (CAx). Computer-aided technologies are the core of product lifecycle management (PLM) and human lifecycle management (HUM). This book has seven chapters, organized in two sections: "Computer-Aided Technologies in Engineering" and "Computer-Aided Technologies in Medicine." The first section treats the different aspects of PLM, including design, simulations and analysis, manufacturing, production planning, and quality assurance. In the second part of the book are presented CAx applications in medicine focused on clinical decision, diagnosis, and biosensor design. CAx plays a key role in a variety of engineering and medical applications, bringing a lot of benefits in product life cycle, extending and improving human life.