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Protein Structure and Modeling
  • Language: en
  • Pages: 276

Protein Structure and Modeling

  • Type: Book
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  • Published: 2019-06-04
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  • Publisher: Springer

This book will consider principles of the organization of protein molecules, the relationships between primary, secondary, and tertiary structure, the determinants of protein conformation, and the applications of structure determination and structure modeling in biomedical research.

SH Domains
  • Language: en
  • Pages: 252

SH Domains

  • Type: Book
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  • Published: 2015-07-17
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  • Publisher: Springer

This book covers structure, function, and important roles of the SH domains, structure-function relationships, the versatile nature of their action, mechanisms of aggregation, specificity of interactions, impact of mutations on protein functional dysregulation, and cell signaling. Their involvement in various cellular processes such as migration, invasiveness, actin reorganization, shaping spines, determination of the morphology assembly of fibrils, and mechanotransduction makes these molecules attractive drug targets. Substrates, inhibitors and activators of PTKs present a wide variety of therapeutic agents in the context of delivering treatments for numerous pathologies. The new emerging field of stem cell therapies and design of biomaterials for treatments relies on the directed regulation of stem cell growth, differentiation and morphology, as well as the production of biomimetic scaffolds that respond to programmed signals. Advances in deciphering the mechanisms of action of these important molecules will lead to the implementation and success of their vital applications.

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions
  • Language: en
  • Pages: 400

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions

A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which m...

Division of Basic Sciences Annual Research Directory
  • Language: en
  • Pages: 476

Division of Basic Sciences Annual Research Directory

  • Type: Book
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  • Published: 1996
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  • Publisher: Unknown

None

Creating New Local Structure Alphabets for Protein Structure Prediction
  • Language: en
  • Pages: 310

Creating New Local Structure Alphabets for Protein Structure Prediction

  • Type: Book
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  • Published: 2010
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  • Publisher: Unknown

None

Division of Basic Sciences Annual Research Directory
  • Language: en
  • Pages: 484

Division of Basic Sciences Annual Research Directory

  • Type: Book
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  • Published: 1996
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  • Publisher: Unknown

None

Directory of Members
  • Language: en
  • Pages: 974

Directory of Members

  • Type: Book
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  • Published: 2002
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  • Publisher: Unknown

None

Telephone and Service Directory
  • Language: en
  • Pages: 502

Telephone and Service Directory

  • Type: Book
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  • Published: Unknown
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  • Publisher: Unknown

None

Digital Transformation on Manufacturing, Infrastructure & Service
  • Language: en
  • Pages: 1031

Digital Transformation on Manufacturing, Infrastructure & Service

This book contains theoretical, econometric, experimental, and policy-oriented contributions of the DTMIS conference participants. Every year the DTMIS conference brings together experts from academia and industry to uncover the challenges and solutions to ensuring digital transformation on manufacturing, infrastructure, and service. The DTMIS proceedings is distinguished by the fact that it contains works not only by scientists, but also by practitioners in the industry, and, of course, their collaboration works are of particular and undeniable value. This book is useful for experienced scientists and practitioners who seek to find something new for themselves and apply it in their work, as well as for students at the beginning of their scientific activity.

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions
  • Language: en
  • Pages: 406

Statistical Mechanics, Protein Structure, and Protein Substrate Interactions

  • Type: Book
  • -
  • Published: 2013-06-19
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  • Publisher: Springer

A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which m...