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Precision Approaches to Heterogeneity in Asthma
  • Language: en

Precision Approaches to Heterogeneity in Asthma

  • Type: Book
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  • Published: 2023-07-27
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  • Publisher: Springer

Asthma has been challenging to treat due to its heterogeneous onset, environmental triggers, severity, and treatment response. To embrace the rapid advances in this field, Precision Approaches to Heterogeneity in Asthma follows its highly successful predecessor, Heterogeneity in Asthma. In this new volume, noted authorities Allan Brasier and Nizar Jarjour and a cadre of leaders in the field incorporate new work advancing our understanding of phenotypes (endotypes) of disease, regional variations in ventilation, systems approach to analyzing the findings from studies of inducible phenotypes, and emerging results of biomarker-informed clinical trials. This work will facilitate our current understanding of the spectrum of disease etiology, prognosis, and the likelihood of responding to the range of available therapeutic interventions.

Precision Approaches to Heterogeneity in Asthma
  • Language: en
  • Pages: 416

Precision Approaches to Heterogeneity in Asthma

Asthma is a common chronic respiratory disease that causes substantial morbidity and has been challenging to treat due to its heterogeneous onset, environmental triggers, severity, and treatment response. To update the field on the rapid advances in this field, Precision Approaches to Heterogeneity in Asthma follows its highly successful predecessor, Heterogeneity in Asthma. In this new volume, noted authorities Allan R Brasier and Nizar N Jarjour and a cadre of leaders in the field incorporate new work advancing our understanding of phenotypes (endotypes) of disease, regional variations in ventilation, systems approach to analyzing the findings from studies of inducible phenotypes, and emerging results of biomarker-informed clinical trials. This work will facilitate our current understanding of the spectrum of disease etiology, prognosis, and the likelihood of responding to the range of available therapeutic interventions.

Severe Asthma
  • Language: en
  • Pages: 360

Severe Asthma

Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Imaging and Functional Imaging of the Lung
  • Language: en
  • Pages: 143

Imaging and Functional Imaging of the Lung

Imaging techniques have been used for decades to detect anomalies, study organ function and for diagnostic purposes. Advances in imaging techniques and image processing as well as a wider availability of lung imaging is providing an increasing amount of data and new insights into lung structure and function and their alterations in common lung diseases. Functional imaging biomarkers have the potential to better characterize individual patient phenotypes, predict disease trajectories, and help personalize therapy. The wealth of new data also confronts us with new challenges in terms of identifying, quantifying, deciphering, and standardizing image-based parameters pertaining to regional lung function.

Navigating Organized Urology
  • Language: en
  • Pages: 215

Navigating Organized Urology

This extensively revised second edition of the text discusses the management of various aspects of the professional life of newly qualified urologists as well as more experienced urologists. It features clear, easy-to-read chapters covering various topics, including clinical and surgical patient care, administrative duties, and research in today's hectic practice environment. New topics covered include how to manage an operating theater, telemedicine and how to manage crisis situations. Lessons acquired from the authors experiences of the COVID-19 Pandemic are also detailed. Navigating Organized Urology: A Practical Guide systematically presents a range of practical strategies for a successful transition from trainee to practicing urologist, while also offering more experienced urologists a fresh perspective on efficient management and successful adaptation of their practices for the modern age.

Therapeutic Targets in Airway Inflammation
  • Language: en
  • Pages: 1000

Therapeutic Targets in Airway Inflammation

  • Type: Book
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  • Published: 2003-05-13
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  • Publisher: CRC Press

This reference examines the cellular, molecular, and genetic mechanisms involved in airway inflammation, as well as the pathophysiology, epidemiology, and aetiology of asthma. It explores strategies to prevent cellular injury and oxidative tissue damage, inhibit key inflammatory pathways and identify disease-specific targets to reduce the induction

Asthma and Rhinitis
  • Language: en
  • Pages: 1021

Asthma and Rhinitis

The second edition of this highly acclaimed text has been extensively revised and greatly expanded to reflect the considerable advances made in our understanding of the mechanisms of asthma and rhinitis. Containing the contributions of 242 experts of international standing, presented in 133 chapters, Asthma and Rhinitis provides an up-to-date, authoritative reference for both the clinician and scientist. The global approach given in this book mirrors the universal approach to the understanding of allergic disease. The editors have carried out a thorough and radical revision of the content by adding 6 new sections and 44 new chapters. Most of this expansion is due to greatly increased coverag...

Lipid Mediators in Allergic Diseases of the Respiratory Tract
  • Language: en
  • Pages: 272

Lipid Mediators in Allergic Diseases of the Respiratory Tract

  • Type: Book
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  • Published: 1994-08-16
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  • Publisher: CRC Press

Audience Postgraduates and researchers in the study of allergies, clinical immunology, chest diseases, pharmacology, physiology, and biochemistry.

The Biological Consequences of Socioeconomic Inequalities
  • Language: en
  • Pages: 290

The Biological Consequences of Socioeconomic Inequalities

Social scientists have repeatedly uncovered a disturbing feature of economic inequality: people with larger incomes and better education tend to lead longer, healthier lives. This pattern holds across all ages and for virtually all measures of health, apparently indicating a biological dimension of inequality. But scholars have only begun to understand the complex mechanisms that drive this disparity. How exactly do financial well-being and human physiology interact? The Biological Consequences of Socioeconomic Inequalities incorporates insights from the social and biological sciences to quantify the biology of disadvantage and to assess how poverty gets under the skin to impact health. Draw...

Clinical Asthma E-Book
  • Language: en
  • Pages: 531

Clinical Asthma E-Book

This unique new text delivers practical guidelines on diagnosing and treating patients with asthma. Drs. Castro and Kraft are extensively involved in asthma research and improved patient care, and their comprehensive coverage of key challenges in diagnosing and treating asthma makes this a must have resource. The organized full-color format ensures readability, and helps you find information quickly and easily. Offers up-to-date protocols and management guidelines to help you provide the best care for your patients. Presents chapters on special situations and special populations to help you overcome clinical challenges such as the difficult-to-control or pregnant asthma patient. Provides spe...