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There has recently been a renewed interest in both casual use of psychedelics as well as experimental use and attempts to discover therapeutic value. There is an effort to recapture the achievements and failures of past work to guide present use. This book is based around material derived from unpublished scientific research from Dr. Robert Mogar’s laboratory and built upon by forty years of field research by the author. The author Niccolo Caldararo participated in a number of studies of perception, including sensory deprivation and psychotropic drugs, some of recent manufacture or discovery and some of primitive or traditional societies. He places this analysis of the physiological aspects of hallucinations, delusions, visions and dreamsn context through an , as well as cross cultural data on dreams, dreaming and drug use and the social value of hallucinations, dreams and visions. The book reviews ethnographic literature in this area and contributes to a comprehensive evaluation of past work done in this area.
This volume explores the latest methods used to study various aspects of TET proteins and their biology. Chapters in this book are divided into five parts. Part One describes technologies aimed at detecting and quantifying DNA methylation turnover using massively parallel sequencing, ELISA, and mass spectrometry approaches. Part Two looks at data analyses protocols for distinguishing acting versus passive DNA demethylation and estimation of 5mC and 5hmC levels. Part Three deals with a new topic that takes advantage of modified CRISPR/Cas9 genome editing systems to target DNA demethylation activity to genomic loci of interest. Part Four discusses protocols that detail how to purify TET protei...
Was würde dein Kind sagen, wenn es seine Gefühle in Worte fassen könnte? »Carina Thiemann lädt Eltern ein, die Welt aus Sicht des Kindes zu sehen und zu denken. Sie eröffnet damit eine neue Perspektive auf den Alltag, aber auch auf viele Fragen, die aus Erwachsenensicht unlösbar scheinen.« Susanne Mierau Carina Thiemann, Pädagogin und reichweitenstarke Gründerin von Weltvonunten, zeigt in ihrem ebenso kenntnisreichen wie einfühlsamen Buch, wie Kinder ihren Alltag erleben: der Wutanfall beim Abendessen nach einem langen Tag in der Kita, der dem Kind viel Kooperation abverlangt hat, das Trödeln beim Umziehen, weil die Gedanken des Kindes noch bei seinem letzten Spiel hängen oder a...
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This volume explores the latest methods used to study various aspects of TET proteins and their biology. Chapters in this book are divided into five parts. Part One describes technologies aimed at detecting and quantifying DNA methylation turnover using massively parallel sequencing, ELISA, and mass spectrometry approaches. Part Two looks at data analyses protocols for distinguishing acting versus passive DNA demethylation and estimation of 5mC and 5hmC levels. Part Three deals with a new topic that takes advantage of modified CRISPR/Cas9 genome editing systems to target DNA demethylation activity to genomic loci of interest. Part Four discusses protocols that detail how to purify TET protei...
This book provides an interesting snapshot of recent advances in the field of single molecule nanosensing. The ability to sense single molecules, and to precisely monitor and control their motion is crucial to build a microscopic understanding of key processes in nature, from protein folding to chemical reactions. Recently a range of new techniques have been developed that allow single molecule sensing and control without the use of fluorescent labels. This volume provides an overview of recent advances that take advantage of micro- and nanoscale sensing technologies and provide the prospect for rapid future progress. The book endeavors to provide basic introductions to key techniques, recent research highlights, and an outlook on big challenges in the field and where it will go in future. It is a valuable contribution to the field of single molecule nanosensing and it will be of great interest to graduates and researchers working in this topic.
The book integrates our understanding of the factors and processes underlying the evolution of multicellularity by providing several complementary perspectives (both theoretical and experimental) and using examples from various lineages in which multicellularity evolved. Recent years marked an increased interest in understanding how and why these transitions occurred, and data from various fields are providing new insights into the forces driving the several independent transitions to multicellular life as well as into the genetic and molecular basis for the evolution of this phenotype. The ultimate goal of this book is to facilitate the identification of general and unifying principles and mechanisms.