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Written by leading statisticians and probabilists, this volume consists of 104 biographical articles on eminent contributors to statistical and probabilistic ideas born prior to the 20th Century. Among the statisticians covered are Fermat, Pascal, Huygens, Neumann, Bernoulli, Bayes, Laplace, Legendre, Gauss, Poisson, Pareto, Markov, Bachelier, Borel, and many more.
An estimated 40 million Americans and millions of others worldwide suffer from some type of sleep disruption or disorder, and these numbers are rapidly increasing. As biomedical technologies advance our understanding of sleep, a wave of developments in sleep research and the emergence of new technologies offer hope and help for a good night‘s
This is a new critical edition of the most widely dispersed and popular Middle English alliterative poems apart from Piers Plowman. It contains a new critical text, based upon all the surviving manuscripts. There is full discussion of the textual relations, and the editorial methods best suited to presenting a text extant in many copies. There are full manuscript descriptions with discussions of sources and possible authorship.
Direct cell–cell communication is a common property of multicellular organisms that is achieved through membrane channels which are organized in gap junctions. The protein subunits of these intercellular channels, the connexins, form a multigene family that has been investigated in great detail in recent years. It has now become clear that, in different tissues, connexins speak several languages that control specific cellular functions. This progress has been made possible by the availability of new molecular tools and the improvement of basic techniques for the study of membrane channels, as well as by the use of genetic approaches to study protein function in vivo. More important, connex...
The recent global financial crisis exposed the serious limitations of existing economic and financial models. Not only did macro models fail to predict the crisis, they seemed incapable of explaining what was happening to the economy. Policymakers felt abandoned by the conventional tools of the now obsolete Washington consensus and the World Trade Organization’s oversimplified faith in free markets.The traditional models for agricultural commodities have so far failed to take into account the uncertain character of the global agricultural economy and its ferocious consequences in food price volatility, the worst in 300 years, yielding hunger riots throughout the world. This book explores t...
This text methodically demonstrates the basic rules for the design criteria of earthfill and rockfill dams. It expertly guides the reader from preliminary work through the design of various embankment dams and on to the construction and finally the control of safety in completed structures.
A quantum leap in technology took place a few years ago with the introduction of cDNA arrays that have been developed in response to the need for simultaneous analysis of the patterns of expression of thousands of genes. DNA Arrays: Technologies and Experimental Strategies offers a view of different aspects of this rapidly developing technology, in
Perspectives in Receptor Research
This authoritative and comprehensive volume presents a perspective in the molecular and cellular diversity of membrane ion channels. Written in an accessible format, it depicts the structure and function of each of the known classes of ion channels. Each chapter provides amino acid sequences, including data base accession numbers; views of secondary, tertiary and quaternary channel structure; and evolutionary relationships among channels.