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The regulation of the organism has traditionally been ascribed to two distinct systems-the nervous and the endocrine. Though coordination between the two systems has been acknowledged, researchers and authors have tended to deal with them as comprising separate categories of cells involved in different activities. With this approach, a given regulatory mechanism would be evaluated as to whether it should be accounted for by nervous or endocrine functions. The past 15 years, however, have witnessed numerous important discoveries and conceptual developments concerning the morphological, physiological, and bio chemical relations between the nervous and endocrine systems. Advances in im munocyto...
The sense of smell is probably the most important sense to a large number of the animal species on Earth and the aim of the study of olfactory cell biology is to understand the cellular basis on which olfactory-driven behaviour is based. In this book the author presents a critical analysis of what is known about the olfactory sensory cells in both the nasal cavity and the vomeronasal organ. Although the emphasis is on mammalian olfaction, basic issues that have been addressed by research on other vertebrates and invertebrates are also discussed. Throughout the book the premise is that we can only more thoroughly comprehend normal behaviour and dysfunction once we have a detailed understanding of the cells and tissues involved in the sense of smell.
A book such as this one necessarily entails the effort of many individuals. Its first seed was a workshop in 1988 that one of us (K. L. C. ) designed and directed at the City University of New York Graduate Center as part of a series of conferences and workshops on topics in neuropsychology spon sored by the Institute for Research in Behavioral Neuroscience (IRBN). At that time, studies in the efficacy of olfaction as an alternative modality of stimulation in brain-injured adults were taking place at IRBN. The work shop helped to spark many new ideas among IRBN's staff, leading to various projects in clinical intervention, some of which are discussed in this volume. We soon discovered that c...
This expanded and updated edition reflects the enormous increase in our knowledge of the development of the nervous system and the use of neural stem cells in clinical applications. Integrating new information about the use of development of neural stem cells for clinical applications, Drs. Rao, Carpenter and Vemuri have added additional chapters on neural transplantation and development of neural stem cells using reprogramming technologies. A new chapter on cancer in nervous system delineates how the fundamental biology of neural stem cells informs our understanding of cancer and tumor formation in the nervous system. Special attention is paid to the derivation of neural cells from embryonic stem cells and induced pluripotent stem cells. Authoritative and up-to-date, Neural Development and Stem Cells, 3rd Edition provides neuroscientists with a handy guide to stem cells in the nervous system, tracing with great clarity the development of stem cells from differentiation to neurons, astrocytes, and oligodendrocytes.
Our senses shape our reality and allow us to adapt to the everlasting changing environment. From all sensory modalities, olfaction is maybe the most intriguing one, probably because olfactory information influences our daily life without us even noticing. However, we can all relate to the powerful impact that the smell of our favorite food has on us. Likewise, olfactory cues could be determinants for partner selection (because love can be blind but not anosmic), mood regulation and cognition. Furthermore, recent studies link early olfactory dysfunctions to the occurrence of devastating pathologies, such as Alzheimer´s and Parkinson´s. Thus, the study of olfaction, at different levels from genetics to behavior, will pave the way for a better understanding of brain processes and associated disorders.
This book provides a comprehensive review of what receptors do in the nervous system, how they do it, the mechanisms by which receptor function is regulated, and the consequences of normal and abnormal receptor function. It contains a series of interrelated chapters describing key neurotransmitter receptors, protein kinases, and protein phosphatases, and details their expression and composition in the development of the central nervous system (CNS).
This edited volume summarizes recent findings of leading researchers investigating the brain systems that underlie memory. The book reviews recent progress in understanding forms of memory in animals and humans and the interaction of cortical and subcortical systems in the regulation of memory. Special emphasis is given to the development of neural network models that attempt to link cells to systems in the representation of memory. The book will be an invaluable source for cognitive psychologists, neuroscientists, and students interested in this active and exciting area of research.
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