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Reflecting the growing volume of published work in this field, researchers will find this book an invaluable source of information on current methods and applications.
Providing the reader with an up to date digest of the most important current research carried out in the field, this volume is compiled and written by leading experts from across the globe. Touching on research areas like exploring the application of electrochemistry in the analysis of chemicals of medical and environmental interest using new materials such as graphene, the development of electrochemical energy storage systems showing how carbon dioxide can be reduced to synthetic fuels, and the application of electrochemical sensors to sensitive and selective determination. The reviews of established and current interest in the field make this book a key reference for researchers in this exciting and developing area.
Set includes revised editions of some issues.
The papers included in this issue of ECS Transactions were originally presented in the symposium ¿Coatings for Corrosion Protection¿, held during the 216th meeting of The Electrochemical Society, in Vienna, Austria from October 4 to 9, 2009.
Community Mental Health Teams (CMHTs) have evolved over the last 30-40 years to serve patients with mental illnesses who would previously have been treated in large mental hospitals. They play a pivotal role in the provision of mental health care in the developed world. Consisting of nurses, doctors, social workers, and psychologists, the people within these teams work together to care for individuals with severe mental illnesses outside the hospital. Because CMHTs have evolved, rather than been developed, little has been written about how they should work - how the multidisciplinary members of the teams can work effectively together, who should do what within the team. This is the first boo...
Epigenetics has emerged recently as an important area of molecular biological studies. Epigenetic modifications lead to potentially heritable but reversible alterations in the expression of genes that determine cell fate. Epigenetic misregulation is thus often linked to degenerative diseases, cancer and neuronal disorders. Recent biomedical interest in this regulatory system stems from the fact that epigenetic, in contrast to genetic, alterations are in principle amenable to pharmacological intervention. A few epigenetically active drugs, for example histone deacetylase inhibitors (HDACi) and DNA methyltransferase (DNMT) inhibitors, have been approved by FDA for treatment of cancers such as CTCL, MDS, and AML. This volume explores the scientific background for clinical applications of epigenetically active drugs. Included are descriptions of epigenetic controls over gene expression, the post-transcriptional silencing of genes by RNA interference (RNAi) and microRNAs, as well as new findings from stem cell research which are relevant to pharmacological applications.
Twenty years after the discovery of neural stem cells, the question whether the central nervous system can be considered among regenerative tissues is still open. On one side, deep characterization of neural stem and progenitor cells, their niches, and their progeny in brain neurogenic sites overtly showed that new neurons can be generated in the brain of adult mammals, including humans. On the other side, many problems arise when stem cells encounter the mature brain parenchyma, still hampering the development of efficacious therapeutic approaches with endogenous or exogenously-delivered neural stem cells. This book tries to make the point on these extremely promising, yet unresolved, issues.
A comprehensive review of advances in one of today's most technologically important research fields. Spurred on by society's increasingly urgent demand for an inexpensive, environment-friendly alternative to the internal combustion engine, research into electrocatalytic fuel cells has yielded many exciting advances in the past few years. This rapid rate of progress, however, has created a daunting challenge for anyone attempting to track the important new trends in electrocatalysis by sorting through the huge and rapidly growing body of world literature in the field. Electrocatalysis was designed to save scientists hours of arduous legwork by providing an authoritative review of the most imp...