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The State of the Art in Transcriptome AnalysisRNA sequencing (RNA-seq) data offers unprecedented information about the transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. RNA-seq Data Analysis: A Practical Approach enables researchers to examine differential expression at gene, exon, and transcript le
This collection contains invited papers by distinguished statisticians to honour and acknowledge the contributions of Professor Dr. Dr. Helge Toutenburg to Statistics on the occasion of his sixty-?fth birthday. These papers present the most recent developments in the area of the linear model and its related topics. Helge Toutenburg is an established statistician and currently a Professor in the Department of Statistics at the University of Munich (Germany) and Guest Professor at the University of Basel (Switzerland). He studied Mathematics in his early years at Berlin and specialized in Statistics. Later he completed his dissertation (Dr. rer. nat. ) in 1969 on optimal prediction procedures ...
This volume contains 3 invited papers, 15 regular papers, and 22 poster papers that were selected for presentation at the Third International Conference on Discovery Science (DS 2000), which was held 4-6 December 2000 in Kyoto. The Program Committee selected the contributed papers from 48 submissions. Three distinguished researchers accepted our invitation to present talks: J- frey D. Ullman (Stanford University), Joseph Y. Halpern (Cornell University), and Masami Hagiya (University of Tokyo). The Program Committee would like to thank all those who submitted papers for consideration and the invited speakers. I would like to thank the Program Committee members, the Local Arrangements Committe...
Demystifies Biomedical and Biological Big Data AnalysesBig Data Analysis for Bioinformatics and Biomedical Discoveries provides a practical guide to the nuts and bolts of Big Data, enabling you to quickly and effectively harness the power of Big Data to make groundbreaking biological discoveries, carry out translational medical research, and implem
This book reviews present state-of-the-art research related to the security of cloud computing including developments in conversational AI applications. It is particularly suited for those that bridge the academic world and industry, allowing readers to understand the security concerns in advanced security solutions for conversational AI in the cloud platform domain by reviewing present and evolving security solutions, their limitations, and future research directions. Conversational AI combines natural language processing (NLP) with traditional software like chatbots, voice assistants, or an interactive voice recognition system to help customers through either a spoken or typed interface. C...
A comprehensive account of joint species distribution modelling, covering statistical analyses in light of modern community ecology theory.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Big Data in Omics and Imaging: Integrated Analysis and Causal Inference addresses the recent development of integrated genomic, epigenomic and imaging data analysis and causal inference in big data era. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), genome-wide expression studies (GWES), and epigenome-wide association studies (EWAS), the overall contribution of the new identified genetic variants is small and a large fraction of genetic variants is still hidden. Understanding the etiology and causal chain of mechanism underlying complex diseases remains elusive. It is time to bring big data, machine learning ...
Physical oncology has the potential to revolutionize cancer research and treatment. The fundamental rationale behind this approach is that physical processes, such as transport mechanisms for drug molecules within tissue and forces exchanged by cancer cells with tissue, may play an equally important role as biological processes in influencing progression and treatment outcome. This book introduces the emerging field of physical oncology to a general audience, with a focus on recent breakthroughs that help in the design and discovery of more effective cancer treatments. It describes how novel mathematical models of physical transport processes incorporate patient tissue and imaging data routi...