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Role of Genomics in the Management of Hypertension
Arterial hypertension affects about 1 billion people worldwide and it is the strongest modifiable risk factor for cardiovascular disease and related disability. Since the initial discovery of rare monogenic disorders with large effects, the role of genomics has evolved into large genome-wide association studies detecting common variants with a modest effect size. Similarly, pharmacogenomics has emerged as a new tool for understanding variability in drug response, to maximize efficacy and reduce toxicity. This book presents the most recent advances in the field of genetics and genomics of arterial hypertension and their potential impact on clinical management. The book is a useful tool for clinicians but also to the research community and those who want to be updated in the field.
Primary Aldosteronism
Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. There are new insights into this matter by using biochemistry as well as advanced radiology. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene – KCNJ5 – in about 40% of PA with adenoma. Chapters in this book include a history of the disorder, epidemiology, genetics derangements, the KCNJ5 mutations and phenotype and more.
Endocrine Hypertension
The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypertension. In Endocrine Hypertension, a renowned panel of experts provides a comprehensive, state-of-the-art overview of this disorder, discussing when to assign an endocrine cause in one of many conditio...
Diabetes Secondary to Endocrine and Pancreatic Disorders
The 1997 classification of diabetes mellitus, now accepted worldwide, includes a large section of ‘Other specific types of diabetes’, a good part of which is made up of diabetes secondary to other endocrine or pancreatic disorders. However, a comprehensive overview on how these disorders may lead to diabetes, and how to diagnose and treat them, was not available so far. Filling this gap, this book includes detailed descriptions of glucose metabolism derangements in other endocrine and pancreatic disorders. Leading experts in their fields present an exhaustive overview of the most-updated evidence on the etiopathological mechanisms underlying the development of diabetes in patients with endocrine and pancreatic disorders, and the relevant diagnostic and therapeutic approaches. Because of its multidisciplinary approach, this book is of great interest to endocrinologists, diabetologists, general practitioners, internal medicine specialists and surgeons, and will remain a reference source for years to come.
Meeting abstracts of the 3° EVIta symposium
The 3rd Symposium of the Italian Society of Extracellular Vesicles (The 3° EVIta Symposium), September 13-15, 2023 [Table 1].
Secondary Hypertension
This book offers an overview of the latest advances in the epidemiological, pathophysiological, diagnostic and therapeutic aspects of secondary hypertension, provided by a group of the most highly respected European experts in this field. It is common belief that secondary forms of hypertension are rare, although in 95% of patients the cause of high blood pressure is unknown – euphemistically referred to as “essential”. There is increasing evidence from epidemiological studies that the prevalence of secondary hypertension is much higher than previously thought, accounting for 20%-25% of all hypertensive patients. There are additional, very good reasons for identifying those patients wi...
Encyclopedia of Endocrine Diseases
Encyclopedia of Endocrine Diseases, Second Edition, Five Volume Set comprehensively reviews the extensive spectrum of diseases and disorders that can occur within the endocrine system. It serves as a useful and comprehensive source of information spanning the many and varied aspects of the endocrine end metabolic system. Students will find a concise description of the physiology and pathophysiology of endocrine and metabolic functions, as well as their diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters explore the latest advances and hot topics that hav...
Netter Collection of Medical Illustrations: Endocrine System E-book
Endocrine System, 2nd Edition provides a concise and highly visual guide to the anatomy, physiology, and pathophysiology of the endocrine glands. This volume in The Netter Collection of Medical Illustrations (the CIBA "Green Books") has been expanded and revised by Dr. William F. Young, Jr. to reflect the many exciting advances that have been made in the field. Classic Netter art, updated illustrations, and modern imaging make this timeless work essential to your library. - Access rare illustrations in one convenient source from the only Netter work devoted specifically to the endocrine system. - Get a complete overview of the endocrine system through multidisciplinary coverage of endocrinol...
NETTER Atlante di anatomia fisiopatologia e clinica: Apparato Endocrino
Collana diretta da Eugenio Gaudio Edizione italiana a cura di Andrea Lenzi Questa seconda edizione è stata pensata per fornire ai medici di qualsiasi livello ed esperienza una guida “visiva sull’anatomia, la fisiologia e la fisiopatologia delle ghiandole endocrine. Il testo è stato completamente riscritto ma la gran parte delle illustrazioni ha resistito alla prova del tempo. Ne sono state aggiunte di nuove in tutte le sezioni poiché, dalla prima edizione ad oggi, sono stati scoperti nuovi disturbi endocrini e nuovi approcci terapeutici. In tutte le tavole è presente una parte di testo che ha la funzione di chiarire e ampliare i concetti presenti nelle immagini. Il volume è organizzato in otto sezioni corrispondenti alle ghiandole e alle componenti del sistema endocrino. Alcuni disegni sono stati integrati con moderne immagini diagnostiche.
Netter Collection, Medizinischer Atlas, Endokrines System
Kurzbeschreibung Die berühmte Netter Collection of Medical Illustrations jetzt in Neuauflage! Nutzen Sie diese einzigartige Sammlung anatomischer Zeichungen zum zuverlässigen und effizienten Nachschlagen! In der Netter Collection - Medizinischer Atlas Endokrines System finden Sie alle hormonproduzierenden Gewebe und Organe: - einprägsam in Wort und Bild dargestellt - topaktuell nach heutigem medizinischen Standard - inkl. aller modernen bildgebenden Verfahren - online-Zugang: Mit dem Code im Buch haben Sie ab Aktivierung Zugriff auf die Abbildungen. Langbeschreibung Die lang ersehnte Neuauflage der Sammlung medizinischer Zeichnungen von Netter liegt nun endlich als medizinischer Atlas vor...
