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In the Matter of Certain Recombinantly Produced Human Growth Hormones
Contents: procedural history; jurisdiction; standard to be applied in issuing temporary relief; parties; importation; products involved; technical issues; technology relating to the subject matter in issue; the Ô619, the Ô832 & the Ô980 patent; non-technical issues (relevant time period; harm to complaint in the absence of TEO relief); balance of 4 factors; bonding; findings of fact (human growth hormone & the Ô619 patent; validity of claims 1,10 & 38 of the Ô619 patent under 35 U.S.C. 103; human growth hormone & the accused BTG process; the Ô980 patent).
LHRH and Its Analogs
Since the discovery of LHRH in 1971, research into the physiology and therapeutics of this compound can be divided into three dis tinctly different phases. In the first phase, attention was paid chiefly to the natural sequence hormone; efforts were channeled to explore its diagnostic use; and nearly all the clinical investigations were coordinated by a single pharmaceutical company. The successes in this area were quite limited and the interest in the promise of this agent as a diagnostic test has long since waned. This phase of research con sumed roughly the first seven years of clinical testing after the isolation and characterization of the compound by the two groups involved in the Nobel...
Molecular Biology of Neuroreceptors and Ion Channels
This workshop was the second of this series held on the island of santorini in the Cycladic Sea. The first one ("Mechanism of Action of the Nicotinic Acetylcholine Receptor", NATO ASI Se ries H, vol. 10) took place in May 1986 and focused on what was at the time the best studied of all neuroreceptors. This second one, held only two years later, demonstrates the im mense progress achieved since then in the field of neurorecep tors and ion channels. Molecular cloning techniques have now made available the primary structures of a whole array of ion channel proteins, and this in turn has shed light on some gen eral principles of the structure-function relationships of these central elements of intercellular communication. The purpose of this workshop was to explore the common ele ments in gene and protein structure of already cloned ion channel proteins, and to assess the status of other cloning projects in progress. It explicitly focused on very recently published and unpublished results. All participants kept to these goals thereby demonstrating the very value of such work shops for the progress of science.
The Dynamic Synapse
Exploring the diverse tools and technologies used to study synaptic processes, The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology delineates techniques, methods, and conceptual advances for studying neurotransmitter receptors and other synaptic proteins. It describes a broad range of molecular, biochemica
Handbook of Receptors and Channels
This authoritative and comprehensive volume presents a perspective in the molecular and cellular diversity of membrane ion channels. Written in an accessible format, it depicts the structure and function of each of the known classes of ion channels. Each chapter provides amino acid sequences, including data base accession numbers; views of secondary, tertiary and quaternary channel structure; and evolutionary relationships among channels.
Surface Engineering of Graphene and Graphene Quantum Dots for Industrial and Medical Applications
This book explores the synthesis, characterization, and applications of graphene and its derivatives. It covers advancements in improving graphene quality, surface engineering methods, and increasing material functionality. The topics covered include functionalized graphene, graphene quantum dots, novel device fabrication approaches, and diverse applications. The book also investigates the fundamental principles of characterizing graphene and its derivatives, along with electronic structures, theoretical investigations, and computational analyses relevant to their applications, synthesis, and properties. The chapters are organized to cover these topics, starting with a general overview of surface chemistry and its concepts for surface engineering of graphene, the fundamental properties of graphene and its derivatives, their synthesis, and applications in numerous fields, and concludes with a future perspective. Significantly, for the first time, both industrial and medical applications are gathered in one book, enabling us to discuss the confrontation of medical and industrial applications of graphene and graphene quantum dots.
Developmental Biology Using Purified Genes
Developmental Biology Using Purified Genes is a compilation of papers presented at the 1981 ICN-UCLA Symposia on Developmental Biology Using Purified Genes, held in Keystone, Colorado. Contributors representing a wide range of disciplines explore the mechanisms underlying gene control of development and explain how purified genes are transcribed in cells, how DNA sequences and non-DNA molecules regulate development, and how gene-control molecules or other developmental determinants are unequally distributed among embryonic cells. Organized into nine sections comprised of 54 chapters, this volume begins with an overview of the mechanism by which gene activity is regionally controlled and its ...
