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Quality of Life
The assessment of patient reported outcomes and health-related quality of life continue to be rapidly evolving areas of research and this new edition reflects the development within the field from an emerging subject to one that is an essential part of the assessment of clinical trials and other clinical studies. The analysis and interpretation of quality-of-life assessments relies on a variety of psychometric and statistical methods which are explained in this book in a non-technical way. The result is a practical guide that covers a wide range of methods and emphasizes the use of simple techniques that are illustrated with numerous examples, with extensive chapters covering qualitative and...
Randomised Clinical Trials
Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials, including developing protocols, data capture, randomisation, analysis and reporting. Assuming no prior background, this user-friendly resource describes the statistical, regulatory, and practical components required for conducting randomised clinical trials. Numerous examples and case studies from industry, academia, and the research literature help readers understand each stage of the clinical trial process. This second edition contains extensively revised material throughout, including new chapters covering designs for repeated measures, non-inferiority...
Oxford Textbook of Oncology
Written by internationally recognized key opinion leaders in all of the oncology sub-disciplines and covering all aspects of the field, the Oxford Textbook of Oncology, Third Edition reflects current best practice and represents a modern approach to managing the cancer patient. This is a definitive resource for oncologists of all varieties.
Evidence-Based Medicine - A Paradigm Ready To Be Challenged?
This open access book aims to clarify the term „evidence-based medicine“ (EBM) from a philosophy of science perspective. The author, Marie-Caroline Schulte discusses the importance of evi-dence in medical research and practice with a focus on the ethical and methodological prob-lems of EBM. The claims that EBM can herald a new theory of epistemology and a Kuhnian paradigm will be refuted. The solution is to describe EBM as a necessary development in medicine to deal with the increasing amount of evidence and medical data without loosing the single patient out of sight.
Dimensional Approach to the conceptualization and measurement of the broad autism phenotype
The present dissertation has converged the knowledge of three fundamental areas of psychology: cognitive psychology, psychobiology, and psychometrics with the purpose of improving the operational and relational definitions of the broad autism phenotype (BAP) and its measurement process. Especially, it lies essence in psychometrics and its role in reconnecting how people show certain milder autistic behaviours with a theoretical and psychometric model capable of representing an operationalization of the construct in the Spanish and English general populations and developing a new measurement tool. This book is organized into three blocks: in the theoretical framework, we define autism (and BA...
Randomized Clinical Trials
Using examples and case studies from industry, academia and research literature, Randomized Clinical Trials provides a detailed overview of the key issues involved in designing, conducting, analysing and reporting randomized clinical trials. It examines the methodology for conducting Phase III clinical trials, developing the protocols, the practice for capturing, measuring, and analysing the resulting clinical data and their subsequent reporting. Randomized clinical trials are the principal method for determining the relative efficacy and safety of alternative treatments, interventions or medical devices. They are conducted by groups comprising one or more of pharmaceutical and allied health...
A Handbook of Practicing Anthropology
An essential career-planning resource, A Handbook of Practicing Anthropology presents a comprehensive account of contemporary anthropological practice written primarily by anthropological practitioners Engagingly written and instructive accounts of practice by anthropological professionals working in corporations, governmental, entrepreneurial, and educational settings Provides essential guidance on applying anthropological principles on the job: what works well and what must be learned Emphasizes the value of collaboration, teamwork, and continuous learning as key elements to success in non-academic careers Highlights the range of successful career options for practitioners , describes significant sectors of professional activity, and discusses key issues, concerns, and controversies in the field Chapters examine key practice sectors such as freelancing, managing a consulting firm, working for government, non-profits, and corporations, and the domains of health, industry, education, international development, and the military
Tutorials in Biostatistics, Statistical Methods in Clinical Studies
The Tutorials in Biostatistics have become a very popular feature of the prestigious Wiley journal, Statistics in Medicine (SIM). The introductory style and practical focus make them accessible to a wide audience including medical practitioners with limited statistical knowledge. This book represents the first of two volumes presenting the best tutorials published in SIM, focusing on statistical methods in clinical studies. Topics include the design and analysis of clinical trials, epidemiology, survival analysis, and data monitoring. Each tutorial is focused on a medical problem, has been fully peer-reviewed and edited, and is authored by leading researchers in biostatistics. Many articles include an appendix on the latest developments since publication in the journal and additional references. This will appeal to statisticians working in medical research, as well as statistically-minded clinicians, biologists, epidemiologists and geneticists. It will also appeal to graduate students of biostatistics.
Patient-Centered Measurement
Patients often are asked to fill out questionnaires before or after going to the doctor's office or hospital. What is the point of these questionnaires? Why do the questions often seem irrelevant? Does it matter if patients fill them out or ignore them? This book addresses these questions while also providing historical context about how these questionnaires became so popular. These questionnaires, which philosopher Leah M. McClimans calls 'Patient-Centered Measures' have a fascinating history that combines the contemporary emphasis in medical ethics on patient-centered care with the contemporary preoccupation with evidence-based medicine (the idea that medical decisions should be based on empirical evidence). Patient-centered measures sit between these two concerns and thus serve as an excellent example of a medical technology for the twenty-first century.
Talking to Your Doctor
The last time you went to your doctor, you might have emerged feeling dissatisfied and disoriented. Nothing was clear after you left the office, and you don’t know whether it’s your fault or the doctor’s. While patients need to take control of the visit and set their agenda, the latest research shows that doctors and patients need to connect on a more emotional level as well. In Talking to Your Doctor, readers will learn to: •Talk to your doctor—and get your doctor to talk to you • Remake the relationship with your doctor, and our health care system, on the basis of good communication •Make sure your visit with the doctor is productive and meets your needs •Help yourself and ...
