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This compendium is intended to be the first updated review of most of the clinical situations that cancer patients may present. It identifies the clinical picture and the therapeutic orientation, with the degrees of recommendation and evidence, as well as the direct bibliographic reference for each statement. We took a multidisciplinary approach, with the collaboration of 261 authors from 9 countries, 45 hospitals and 19 medical and non-medical specialties. This compendium (IOC 2022) is the result of the effort and innovative spirit of its authors, will be updated every two years. The first international edition of cancer care support based on real world evidence (RWE) contains all the latest news in cancer care support treatment and assigns levels of evidence and grades of recommendation so that the reader can obtain a quick impression and certainty of each of the treatments and strategies presented. The GRADE and OXFORD scales have been used for the levels of evidence.
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