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Microarray Technology in Practice
Using chips composed of thousands of spots, each with the capability of holding DNA molecules corresponding to a given gene, DNA microarray technology has enabled researchers to measure simultaneously gene expression across the genome. As with other large-scale genomics approaches, microarray technologies are broadly applicable across disciplines of life and biomedical sciences, but remain daunting to many researchers. This guide is designed to demystify the technology and inform more biologists about this critically important experimental technique. - Cohesive overview of the technology and available platforms, followed by detailed discussion of experimental design and analysis of microarray experiments - Up-to-date description of normalization methods and current methods for sample amplification and labeling - Deep focus on oligonucleotide design, printing, labeling and hybridization, data acquisition, normalization, and meta-analysis - Additional uses of microarray technology such as ChIP (chromatin immunoprecipitation) with hybridization to DNA arrays, microarray-based comparative genomic hybridization (CGH), and cell and tissue arrays
e-Health Care in Dentistry and Oral Medicine
This clinically oriented book presents the state of the art in e-health care within dentistry and oral medicine (“e-oral health”) with the aim of acquainting dentists and other oral health care professionals with its uses and advantages, especially with regard to diagnosis. It will assist all who wish to learn about teledentistry protocols and the e-oral health branch or to implement e-oral health solutions and procedures in clinical practice. The book opens by discussing general aspects of e-oral health, including tools, networks, and the very important ethical considerations. The use and specific benefits of e-oral health technologies in the diagnosis of different conditions, orthodontic assessment, implantology evaluation, and caries prevention are then fully explained. Finally, examples are provided of the ways in which teledentistry functions in different countries on different continents. e-Oral health is a burgeoning field that encompasses teledentistry as well as other uses of information and communication technologies for oral health care purposes. This book will be an ideal guide for not only dentists but also dental hygienists, dental nurses, and other professionals.
Respiratory Regulation - The Molecular Approach
This book, an international collaborative effort in the area of molecular respiratory research, showcases a broad range of multidisciplinary approaches to unravel and analyze the underlying mechanisms of a spectrum of respiratory ailments. It discusses immunological and genetic respiratory disorders, cancer, respiratory allergies and cough, sleep disordered breathing and many others. Exciting new results and up-to-date critical overviews of widely debated topics pertaining to respiratory disorders are presented. The contributions provide evidence for the growing interest of the international community of researchers in the field of respiration. The book incorporates modern molecular approaches to diagnostic and treatment solutions, underscoring the need for rational, evidence-based treatment methods. Combining cutting edge basic and clinical research with expert knowledge and experience this book is essential reading for medical students, research scientists and practicing specialists in pulmonology, immunology and allergology.
Tutorials in Endovascular Neurosurgery and Interventional Neuroradiology
This book aims to provide the trainee and practicing minimally invasive neurological therapist with a comprehensive understanding of the background science and theory that forms the foundation of their work. The contents are based on the tutorial teaching techniques used at the University of Oxford and are authored by the MSc Course Director. The tutorial is a learning episode focussed on a particular topic and intended to guide the student/reader through the background literature, to highlight the research on which standard practices are based and to provide the insights of an experienced practitioner. Each chapter of the book covers a different topic to build a complete review of the subspecialty, with in-depth discussion of all currently used techniques. The literature is reviewed and presented in context to illustrate its importance to the practice of this rapidly expanding field of medical treatment.
The Mind of the Horse
Horses were first domesticated about 6,000 years ago on the vast Eurasian steppe, yet only in the last two decades have scientists begun to explore the mental capacities of these animals. In The Mind of the Horse, Michel-Antoine Leblanc presents an encyclopedic synthesis of scientific knowledge about equine behavior and cognition, providing experts and enthusiasts alike with an up-to-date understanding of how horses perceive, think about, and adapt to their physical and social worlds. Much of what we think we know about "the intelligence of the horse" derives from fragmentary reports and anecdotal evidence. Putting this accumulated wisdom to the test, Leblanc introduces readers to rigorous e...
Management of Legionella in Water Systems
Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.
Equine Podiatry
Intended for veterinarians and farrier's, this book focuses on the foot, which is the most common site of lameness in horses. It covers the basic farrier principles, and focuses on medical and surgical foot care management. It includes information on the anatomy and physiology of the equine foot, pathological conditions, and more.
Enhancing Academic Research and Higher Education With Knowledge Management Principles
Knowledge management principles, strategies, models, tools, and techniques have been proven in government, business, and industry. More recently, knowledge management has emerged as an essential enabler for the successful pursuit of scholarly activities in higher education. Knowledge management has significant contributions to make in capturing, storing, processing, and disseminating knowledge between and across these stakeholder entities and their processes to better support these interrelated processes and activities. Given the impetus provided by the United Nations Global Knowledge Economy Policy, institutions worldwide are actively pursuing the use of knowledge management in all facets o...
