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Dirk van Dalen’s biography studies the fascinating life of the famous Dutch mathematician and philosopher Luitzen Egbertus Jan Brouwer. Brouwer belonged to a special class of genius; complex and often controversial and gifted with a deep intuition, he had an unparalleled access to the secrets and intricacies of mathematics. Most mathematicians remember L.E.J. Brouwer from his scientific breakthroughs in the young subject of topology and for the famous Brouwer fixed point theorem. Brouwer’s main interest, however, was in the foundation of mathematics which led him to introduce, and then consolidate, constructive methods under the name ‘intuitionism’. This made him one of the main prot...
Introduces professionals and scientists to statistics and machine learning using the programming language R Written by and for practitioners, this book provides an overall introduction to R, focusing on tools and methods commonly used in data science, and placing emphasis on practice and business use. It covers a wide range of topics in a single volume, including big data, databases, statistical machine learning, data wrangling, data visualization, and the reporting of results. The topics covered are all important for someone with a science/math background that is looking to quickly learn several practical technologies to enter or transition to the growing field of data science. The Big R-Bo...
At the end of the initial meeting on Primary and Secondary Metabolism of Plant Cell Cultures at Schloss Rauischholzhausen, it was decided to convene similar events on a regular basis midway between the International Congress for Plant Tissue and Cell Cul ture. We felt it was necessary to bring representatives of the research teams working in this field together to assess progress as well as to discuss future directions. The Plant Biotechnology Institute of the National Research Council of Canada in Saskatoon, Saskatchewan was chosen to be the site for the second symposium held in 1988. The theme of this meeting was "The Regulation of Primary and Secondary Metabol ism in Plant Cells" and judg...
The story begins in Europe, with a brief history of the church out of which the Reformation grew. The scene then shifts to New Amsterdam in 1628, where a miniscule church survived the English conquest and eventually grew into the Reformed Church in America. By Grace Alone follows its story into the twenty-first century. In addition to the sequential story of the Reformed Church's development, there are vignettes of people involved in events small and great - from the diary of a frail young woman who survived near calamity at sea but ended her life at eighty-one, the widow of the president of Queen's College, to the boy from a farm in Iowa who built the Crystal Cathedral. The reader will also be helped by timelines in every chapter, as well as a glossary, an index, and many illuminating illustrations.
As a low-lying delta region with a high population density, the Netherlands has long focused on the prevention of flooding catastrophes and the reclamation of valuable land. The evolution of Dutch water governance, beginning with the creation of local 'water boards' in the Middle Ages and growing into a complex infrastructure of polders, dams, and controlled waterways offers a compelling study of pitfalls and successes within one of the worlds most challenging regions for water management. Water Policy in the Netherlands traces the arc of water governance in the country, from technological innovations to prevent wide-scale flooding, to strategies focused primarily on improving water quality,...
This book is a summary of the presentations and discussions at the Workshop on Methods of Pesticide Exposure Assessment held in Ottawa, Canada, on October 5-8, 1993. The event was a joint effort of Health Canada and the North Atlantic Treaty Organisation and was officially supported by the United States Environmental Agency and the Organisation for Economic Co-operation and Development (OECD). The goal of the workshop was to examine current issues in the field of pesticide exposure assessment with the aim of reaching an internationally harmonized approach to methods of exposure assessment. With regulatory agencies of OECD Member countries moving towards the harmonization of data requirements...
Although dermatomyositis is a rare connective tissue disease, many physicians are confronted with the diagnosis and treatment of patients affected by this condition. Based on the vast personal experience of the authors, who have diagnosed, treated, and managed many dermatomyositis patients, this clinical guide provides dermatologists, rheumatologists, pediatricians, neurologists, and general practitioners with the keys to interpreting the clinical symptoms of dermatomyositis. Also included are algorithms to help the reader to make the correct diagnosis, as well as guidance on new diagnostic methods and treatment schemes.