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Recent developments in surgical techniques have led to an increased demand for bone stock. Fusion enhancement, bone-void filling in tumor surgery and trauma are only a few examples. Autologous bone can be considered as the most successful bone graft material, and constitutes the accepted 'gold standard', as it combines all the properties required from the bone graft. In this book a 'state of the art in bone substitution for the spine' is presented. The general principles of bone biology and bone healing are outlined, as are recent advances in understanding and influencing bone formation. A variety of substitutes are described and compared.
Over the past decade, there has been rapid growth in bioengineering applications in the field of spine implants. Spine Technology Handbook explains the technical foundation for understanding and expanding the field of spine implants, reviews the major established technologies related to spine implants, and provides reference material for developing and commercializing new spine implants. The editors, who have a track record of collaboration and editing technical books, provide a unified approach to this topic in the most comprehensive and useful book to date. Related website provides the latest information on spine technology including articles and research papers on the latest technology and development Major technologies reviewed include devices used for fusion (screws, plates, rods, and cages), disc repair and augmentation, total disc replacement, and vertebral body repair and augmentation Technology landscape, review of published/public domain data currently available, and safety and efficacy of technology discussed in detail
The first of its kind, Neck and Arm Pain Syndromes is a comprehensive evidence- and clinical-based book, covering research-based diagnosis, prognosis and management of neuromusculoskeletal pathologies and dysfunctions of the upper quadrant, including joint, muscle, myofascial and neural tissue approaches. It uniquely addresses the expanding role of the various health care professions which require increased knowledge and skills in screening for contra-indications and recognizing the need for medical-surgical referral. Neck and Arm Pain Syndromes also stresses the integration of experiential knowledge and a pathophysiologic rationale with current best evidence. - the only one-stop guide for e...
Joint replacement is a logical step in the treatment of severe joint pathologies with irreversible lesions resisting conservative therapy. At the spinal level, arthrodesis became, very early, the gold standard of treatment for severe intervertebral disc pathologies. The next logical step was to envision functional replacement, and this step was taken as early as 1956, when the first intervertebral implant was described. However, it took many more years and a great variety of proposed implant designs before clinical applications could be attempted.
Monoclonal antibodies are antibody molecules having homogeneous structure and known specificity. This book provides a basic and over all idea of research carried out in the field of monoclonals for the past three decades. This book discusses in detail the production of monoclonalanti bodies, the techniques used to make human monoclonals, the wide applications of monoclonals in various fields like medical,environmental, industrial and research and the FDA-approved monoclonal drugs with respect to their nature, their modes of action, and the experiments undertaken during their clinical trials, with appropriatediagrams and graphic illustrations. The book also discusses the research undertaken by various biotech companies, patents applied, and the present and future status of monoclonals in the drug market.
- Comprehensive, up-to-date textbook on the imaging of frequently encountered spinal disorders - Richly illustrated - All imaging modalities considered, e.g. plain film, multidetector CT and MRI - Designed to ensure ease of use, with a logical structure and extensive index