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Encyclopedia of Production and Manufacturing Management
The Encyclopedia of Production and Manufacturing Management is an encyclopedia that has been developed to serve this field as the fundamental reference work. Over the past twenty years, the field of production and operations management has grown more rapidly than ever and consequently its boundaries have been stretched in all directions. For example, in the last two decades, production and manufacturing management absorbed in rapid succession several new production management concepts: manufacturing strategy, focused factory, just-in-time manufacturing, concurrent engineering, total quality management, supply chain management, flexible manufacturing systems, lean production, and mass customi...
Hearings
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Molecular Medicine
Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances. Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine The only book in Molecular Medicine to reach its fourth edition Identifies current practice as well as future developments Presents extensive tables, well presented figures and resources for further understanding
New Research in Cognitive Sciences
Cognitive science is most simply defined as the scientific study either of mind or of intelligence. It is an interdisciplinary study drawing from relevant fields including psychology, philosophy, neuroscience, linguistics, anthropology, computer science, biology, and physics. There are several approaches to the study of cognitive science. These approaches may be classified broadly as symbolic, connectionist, and dynamic systems. Symbolic -- holds that cognition can be explained using operations on symbols, by means of explicit computational theories and models of mental (but not brain) processes analogous to the workings of a digital computer. Connectionist (subsymbolic) -- holds that cognition can only be modelled and explained by using artificial neural networks on the level of physical brain properties.
Modern Molecular Biology:
Molecular biology has rapidly advanced since the discovery of the basic flow of information in life, from DNA to RNA to proteins. While there are several important and interesting exceptions to this general flow of information, the importance of these biological macromolecules in dictating the phenotypic nature of living creatures in health and disease is paramount. In the last one and a half decades, and particularly after the completion of the Human Genome Project, there has been an explosion of technologies that allow the broad characterization of these macromolecules in physiology, and the perturbations to these macromolecules that occur in diseases such as cancer. In this volume, we wil...
Endotoxins: Structure, Function and Recognition
Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death. This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases. The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.
Official Register
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Bacterial Lipopolysaccharides
The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work. Central emphasis is placed upon the fine chemical structure of the lipopolysaccharide and its significance for understanding their activity and function. In particular, the role it plays in the interaction of bacteria with other biological systems is examined. New aspects of their physicochemical biology are introduced and updates to the current knowledge concerning the lipopolysaccharide are provided. This important class of biomolecules has recently attracted the attention of many investigators, in particular for understanding its involvement in innate immunity, toll-like receptor recognition and intracellular signaling.
