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Toxins and Hemostasis
  • Language: en
  • Pages: 790

Toxins and Hemostasis

Circulation of blood is vital for the survival of vertebrates, including man. Mainly, it plays an important role in carrying food nutrients and oxygen to every tissue and organ and in removing all waste products and carbon dioxide. Any imbalance in the hemostatic and cardiovascular systems can lead to death and severe debility. A number of animals have developed mechanisms to target these systems and exploit the vulnerability. In some species (for example, snakes), such mechanisms are used to immobilize and kill the victim/prey, whereas in others (for example, insects, such as leaches, mosquitoes and ticks), they are used to provide a continuous supply of blood. These mechanisms include, but...

  • Language: en
  • Pages: 365

"Venomous Bites from Non-Venomous Snakes

  • Type: Book
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  • Published: 2011-06-20
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  • Publisher: Elsevier

This book is the first significant contribution to thoroughly examine the potential hazards associated with snakes of the former family, Colubridae. This family contained >65% of living snake species (approximately 3,000 taxa) and has recently been split into multiple families. Many of these snakes produce oral secretions that contain toxins and other biologically-active substances. A large variety of these snakes figure in the pet industry, yet little documented information or formal study of their potential medical importance has been published. Therefore, although the possible medical importance of many of these species has been subjected to speculation since the mid-nineteenth century, t...

Index Medicus
  • Language: en
  • Pages: 2324

Index Medicus

  • Type: Book
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  • Published: 2004
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  • Publisher: Unknown

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

The Origin and Early Evolutionary History of Snakes
  • Language: en
  • Pages: 489

The Origin and Early Evolutionary History of Snakes

Latest developments in understanding how, when and where the extraordinary body plan and ecology of snakes evolved from lizard ancestors.

Handbook of Venoms and Toxins of Reptiles
  • Language: en
  • Pages: 681

Handbook of Venoms and Toxins of Reptiles

  • Type: Book
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  • Published: 2021-05-24
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  • Publisher: CRC Press

A decade after publication of the first edition, Handbook of Venoms and Toxins of Reptiles responds to extensive changes in the field of toxinology to endure as the most comprehensive review of reptile venoms on the market. The six sections of this new edition, which has nearly doubled in size, complement the original handbook by presenting current information from many of the leading researchers and physicians in toxinology, with topics ranging from functional morphology, evolution and ecology to crystallography, -omics technologies, drug discovery and more. With the recent recognition by the World Health Organization of snakebite as a neglected tropical disease, the section on snakebite ha...

Animal Toxins
  • Language: en
  • Pages: 376

Animal Toxins

  • Type: Book
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  • Published: 2013-12-01
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  • Publisher: Birkhäuser

This manual surveys toxins from insects, spiders, mollusks, fish, and snakes which have biotechnological applications. It reviews aspects of toxin origin, their molecular mechanism, and their cellular and pathogenic effects. It also provides methodology for the application of these toxins in the research laboratory. This includes a description of the extraction methods, biochemical characterization, and applications in pharmacological studies.

Identification and Functional Characterization of Novel Venom Components
  • Language: en
  • Pages: 210

Identification and Functional Characterization of Novel Venom Components

  • Type: Book
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  • Published: 2020-12-29
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  • Publisher: MDPI

Throughout most of the 20th century, the toxinological literature consisted largely of pharmacological and functional characterizations of crude venoms and venom constituents, often constituents that could not be identified unambiguously. The advent of amino acid composition analysis in the 1950s enabled the first forays into physical characterizations of purified toxins, though these remained few in number until the 1970s. Then, the tryptic and chymotryptic cleavage of venom proteins coupled with manual Edman degradation began to provide the first complete sequences, particularly of three-finger toxins. Polyacrylamide gel electrophoresis and improved resins for liquid chromatography permitt...

Official Gazette of the United States Patent and Trademark Office
  • Language: en
  • Pages: 1416

Official Gazette of the United States Patent and Trademark Office

  • Type: Book
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  • Published: 2001
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  • Publisher: Unknown

None

Venoms to Drugs
  • Language: en
  • Pages: 338

Venoms to Drugs

This unique book will provide an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. Topics cove...

Snake Venom Metalloproteinases
  • Language: en
  • Pages: 277

Snake Venom Metalloproteinases

  • Type: Book
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  • Published: 2018-07-10
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  • Publisher: MDPI

This book is a printed edition of the Special Issue "Snake Venom Metalloproteinases" that was published in Toxins