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Biological Response Mediators and Modulators explains that the behavior of a cell depends upon the absorption of the ligand, the quantity of functional receptors existing for ligand recognition and binding, and the transduction of the signal through successive intercellular events. The book presents such model systems as the low-density lipoprotein (LDL) receptor, the epidermal growth factor receptor, and the insulin receptor. The LDL receptor is a model for a class of surface receptors that facilitate the cellular application of macromolecules through the process of receptor-mediated endocytosis. The book discusses the general characteristics of receptor-mediated endocytosis. Another topic of interest is the property of growth-related cell surface receptors. The section that follows describes the function of these receptors as tyrosine-specific protein kinases, which is related to the protein yields of some viral oncogenes. The amount of receptors in a cell depends upon the rates of synthesis and inactivation. The book will provide valuable insights for scientists, cytologists, students, and researchers in the field of chemistry.
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from those cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular sys tem. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowle...
The execution of detailed studies on the fate and levels of hazardous elements in the environment, foodstuffs and in human beings has become a major task in environmental research and especially in analytical chemistry. This has led to a demand to develop new methodology and optimize that already in use. The book offers the reader a general introduction to the problem areas that are currently being tackled, followed by chapters on sampling and sample preservation, strategies and applications of the archiving of selected representative specimens for long-term storage in environmental specimen banks. This is supplemented by the example of wine as a preserved - frequently, already historical - ...
This book consists of invited reviews written by world-renowned experts on the subject of the outskirts of galaxies, an upcoming field which has been understudied so far. These regions are faint and hard to observe, yet hide a tremendous amount of information on the origin and early evolution of galaxies. They thus allow astronomers to address some of the most topical problems, such as gaseous and satellite accretion, radial migration, and merging. The book is published in conjunction with the celebration of the end of the four-year DAGAL project, an EU-funded initial training network, and with a major international conference on the topic held in March 2016 in Toledo. It thus reflects not o...
This book contains an up-to-date review of the structure and evolution of disk galaxies from both the observational and theoretical point of view. It is the proceedings of the "Island Universes" conference held at the island of Terschelling in July 2005. It brings together a broad range of aspects of disk galaxies: structure and dynamics, the latest multi-wavelength surveys, low- and high redshift observations, theory and observations.
Includes section, "Recent book acquisitions" (varies: Recent United States publications) formerly published separately by the U.S. Army Medical Library.
This thesis represents the first wide-field photometric and spectroscopic survey of star clusters in the nearby late-spiral galaxy M33. This system is the nearest example of a dwarf spiral galaxy, which may have a unique role in the process of galaxy formation and evolution. The cold dark matter paradigm of galaxy formation envisions large spiral galaxies, such as the Milky Way, being formed from the merger and accretion of many smaller dwarf galaxies. The role that dwarf spiral galaxies play in this process is largely unclear. One of the goals of this thesis is to use the star cluster population of M33 to study its formation and evolution from its early stages to the present. The thesis presents a new comprehensive catalog of M33 star clusters, which includes magnitudes, colors, structural parameters, and several preliminary velocity measurements. Based on an analysis of these data, the thesis concludes that, among other things, the evolution of M33 has likely been influenced by its nearby massive neighbor M31.