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Hyde Park
The story of London’s favourite Royal Park and neighbouring Kensington Gardens, beautifully illustrated with paintings, prints, postcards and modern photographs.
The Causes and Consequences of Chromosomal Aberrations
The Causes and Consequences of Chromosomal Aberrations explores one of the most dramatic examples of genomic instability-chromosomal aberrations. It describes some of the more recent techniques used to map genes within the human genome, study chromosomal aberrations at the cellular level, and define the organization of the interphase nucleus. General overviews are provided to build a conceptual framework for understanding the generality and specificity of chromosomal aberrations. The Causes and Consequences of Chromosomal Aberrations also explores the role of recombinases and topoisomerases in the development of chromosomal aberrations. It contains studies of chromosomal aberrations, which offer separate instructive treatises on specific malignancies. The Causes and Consequences of Chromosomal Aberrations is useful to medical and graduate students, physicians, molecular biologists, and cytogeneticists. It will benefit anyone interested in the concepts, contributions, and development in the field of molecular cytogenetics.
Transcription Factors
Transcription Factors Normal and Malignant Development of Blood Cells Katya Ravid and Jonathan Licht The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification...
Cotherstone: A Village in Teesdale
This fascinating history of the village of Cotherstone in Teesdale will be of interest to all those who have lived in the village or know it well.
Advances in Immunology
Celebrating the publication of our fiftieth volume.
Sir Christopher Wren
Sir Christopher Wren (1632–1723) is now mostly remembered as a genius of architecture – but he was also an accomplished polymath, who only came to architecture quite late in life. Most famous as the mastermind behind the rebuilding of St Paul's Cathedral and more than fifty parish churches after the Great Fire of London, among his countless other projects Wren also designed the Royal Hospital at Chelsea, the Royal Naval Hospital at Greenwich, and much of Hampton Court Palace. Replete with colourful images of his buildings, this concise biography tells the story of a man whose creations are still popular tourist attractions to this day, but also casts light on Wren's credentials as an intellectual and a founding member of the Royal Society.
The Molecular Biology of Autoimmune Disease
Autoimmune diseases are common and often associated with considerable morbidity or - in diseases such as IDDM, myasthenia gravis and multiple sclerosis - mortality. In this volume, experts of international stature in basic science and clinical medicine with a common interest in understanding the normal and aberrant immune response present their experiences. It was their intention to fur- ther the understanding of potential clinical application of scientific observations and to help to comprehend the huge amount of results in autoimmunity research.
