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Cerebral Small Vessel Disease and Cerebral Amyloid Angiopathy
Sporadic cerebral small vessel disease (SVD) is considered to be among the most commonly known neuropathological processes in the brain, hosting a crucial role in stroke, cognitive impairment, and functional loss in elderly subjects. We investigated clinical (neuroimaging and cognitive) biomarkers in the SVD, through a series of analyses from our five studies. Sporadic cerebral SVD is a complex 'micro-world' to be globally considered. All the relevant lesion types and SVD neuroimaging burden should be taken into account. The cumulative effects of microangiopathy burden in the brain of patients affected by SVD are crucial. Cognitive rehabilitation could represent a promising approach to prevent vascular dementia or to improve cognitive performances in patients with cerebral SVD. Longitudinal studies may provide more robust information about the progression and prognostic significance of our findings.
Fascist Voices
A history of fascist Italy draws on private diaries, letters, and memoirs to show how ordinary people lived and experienced Mussolini's regime leading up to World War II.
Ischemic Stroke Therapeutics
This complete resource captures state-of-the-art strategies and the accelerated pace of discovery that is revolutionizing what is known about ischemic stroke and its treatment. Therapeutics for acute management, secondary prevention, recovery, rehabilitation, asymptomatic cerebral ischemia, and implementation of stroke systems of care are all discussed in this comprehensive yet practical guide. Chapters are authored by leading academicians with extensive clinical practice experience from all over the world and feature the scientific evidence behind prevailing therapeutic strategies for managing ischemic cerebrovascular disease. The specialist or general practitioner will gain critical knowledge in stroke management, current clinical challenges and promising new therapies under investigation.
Intramural Vascular Cells: Key Therapeutic Targets for Vascular Cognitive Impairment
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Il popolo del Duce
Esprimere gratitudine, avanzare una supplica, dimostrare la propria fede, chiedere favori o un aiuto economico, ma anche esprimere al proprio leader ammirazione incondizionata, fino al desiderio amoroso o all'adorazione religiosa. Durante il ventennio migliaia di italiani impugnarono la penna per scrivere al loro capo carismatico. Per tanti il culto del Duce non fu soltanto il prodotto della propaganda ma un attaccamento profondamente sentito. Christopher Duggan ricostruisce il ventennio dagli albori dello squadrismo sino alla caduta del regime, attraverso una documentazione fatta di lettere e diari privati inediti, resoconti giornalistici, programmi radio, canzoni popolari. La straordinaria relazione intimache moltissimi italiani intrattennero con Mussolini racconta una storia emotiva dell'Italia fascista che corre sotterranea e parallela lungo i binari degli avvenimenti storici.
Las inéditas
El libro consiste en una recopilación de artículos desarrollados por especialistas procedentes de diferentes áreas de conocimiento, implicados en la misión de reconstruir el canon literario. Nuestra motivación principal es colmar el vacío existente en los estudios literarios recuperando escritoras olvidadas o silenciadas a lo largo de la historia, a pesar de la apreciable calidad artística y la incuestionable importancia sociocultural de sus obras. Cabe destacar también la existencia de autoras emergentes que aún no han conseguido hacerse un hueco en el panorama editorial en lengua española. Confiamos en que la presente obra pueda constituir un paso importante para dar visibilidad a las biografías y a los textos de estas mujeres desmontando tópicos y superando prejuicios.
I professionisti chimici
Durante tutto il Novecento la scienza e l’industria chimica, correlate al mondo economico, sono state protagoniste dei progressi che hanno contribuito a migliorare la qualità della nostra vita e di tutta la società. Anche in Italia l’azione di consulenza del professionista chimico è stata determinante: nella ricerca, nell’industria e nel sapersi rapportare con gli organismi della società. Questo volume mette a disposizione del lettore un quadro completo delle attività degli Ordini dei Chimici, dal loro apparire e per quasi un secolo di vita italiana, in una complessità di rapporti con le vicende istituzionali, politiche ed economiche del Paese. Presenta una puntuale rassegna cronologica di fatti, una galleria di figure protagoniste, una diligente trascrizione di documenti, tutto raccolto e ordinato con la competenza di chi ha vissuto la propria vita militando nella professione del chimico.
Benedict XIV and the Enlightenment
Benedict XIV and the Enlightenment offers a comprehensive assessment of Benedict's engagement with Enlightenment art, science, spirituality, and culture.
The Importance Of Iron In Pathophysiologic Conditions
The iron element (Fe) is strictly required for the survival of most forms of life, including bacteria, plants and humans. Fine-tuned regulatory mechanisms for Fe absorption, mobilization and recycling operate to maintain Fe homeostasis, the disruption of which leads to Fe overload or Fe depletion. Whereas the deleterious effect of Fe deficiency relies on reduced oxygen transport and diminished activity of Fe-dependent enzymes, the cytotoxicity induced by Fe overload is due to the ability of this metal to act as a pro-oxidant and catalyze the formation of highly reactive hydroxyl radicals via the Fenton chemistry. This results in unfettered oxidative stress generation that, by inducing protei...
The Art Market in Rome in the Eighteenth Century
Recent interest in the economic aspects of the history of art have taken traditional studies into new areas of enquiry. Going well beyond provenances or prices of individual objects, our understanding of the arts has been advanced by research into the demands, intermediaries and clients in the market. Eighteenth-century Rome offers a privileged view of such activities, given the continuity of remarkable investments by the local ruling class, combined with the decisive impact of external agents, largely linked to the Grand Tour. This book, the result of collaboration between international specialists, brings back into the spotlight protagonists, facts and dynamics that have remained unexplored for many years.
