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Indian Herbal Medicines
This book discusses the scope and limitations of the antimicrobial and antioxidant properties of foods as medicines or medicinal coadjuvants in traditional Indian herbal therapies. The first chapter introduces readers to the relevance of the Ayurveda system, its holistic classification approach, applications of selected herbs and the demonstrable efficacy of herbal extracts in terms of antimicrobial susceptibility. In turn, the second chapter discusses the antimicrobial properties and kinetic mechanisms of inhibition ascribed to selected vegetable extracts. The third chapter addresses the antioxidant power of phenolic compounds from vegetable products and herbal extracts. The book closes with a review of natural antioxidant agents’ role in the treatment of metabolic disorders. Written from an Indian perspective, this book unravels the chemistry of the traditional Indian diet and its impact on health. Further, it can serve as a reference for other traditional products with similar health claims.
Nanoarchitectonics for Brain Drug Delivery
This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoreti...
Trends in Food Chemistry, Nutrition and Technology in Indian Sub-Continent
This brief outlines the state-of-art of the food industry within the Indian Sub-continent, providing a detailed insight into the current science of nutrition and industrial technology. The Hygiene, Integrity, Traceability and Sharing (HITS) strategy has been proposed recently as a coordinated and powerful tool to contextualize the plethora of different menaces for the food consumer. The book examines this approach from eight different perspectives, with a particular emphasis on the Indian Subcontinent. Topics such as food additives, the importance of water in the food industry, the use of antioxidants, and novel food preservation methods are used to illustrate these points of view. This book is particularly appealing as a guide for graduate and undergraduate courses covering food production, food safety, and the training of teachers working in these science areas.
Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective
Nanotechnology has revolutionized cancer diagnosis and therapy through targeted drug delivery. Advances in protein engineering and materials science have led to the development of nanocarriers (NCs), which have helped overcome the challenges faced during conventional cancer treatment. These nanocarriers serve as an efficient transport module for drugs. Nano-drug delivery has emerged as a promising technology that results in early detection and better treatment of various cancers. The approved nanoparticles currently used in cancer treatment strategies include liposomes, dendrimers, polyplexes, solid lipid nano-carriers, etc. These nanocarriers can potentially provide a quick, safe, and cost-...
Artificial Intelligence in Medical Virology
This book comprehensively reviews the potential of Artificial Intelligence (AI) in biomedical research and healthcare, with a major emphasis on virology. The initial chapter presents the applications of machine learning methods for structured data, such as the classical support vector machine and neural network, modern deep learning, and natural language processing for unstructured data in biomedical research and healthcare. The subsequent chapters explore the applications of AI in tackling COVID-19, analysis of the pandemic, viral infection, disease spread, and control. The book further identifies the potential applications of machine learning in the field of virology with a focus on the ke...
Specialized Metabolites from Medicinal Plants: the Structural Identification, Biological Activity and Biosynthesis Pathways
Morphine, extracted/isolated from the opium poppy, was the first plant-derived natural product, which was first reported in 1806 and marked as the beginning of plant metabolites research. In the following 200 years, many specific metabolites with significant bio-activity, such as quinine, artemisinin, and paclitaxel, were discovered in plant-derived medicines and have been used for treating human diseases. The extracts of plants or their metabolites have contributed significantly to human health, particularly in the treatment of chronic diseases such as diabetes, hypertension, and obesity. Nowadays, medicinal plants and their metabolites are increasingly favored by researchers and pharmaceutical companies to be developed as new dietary supplements and pharmaceuticals. Therefore, screening and identification of novel active metabolites or lead compounds from plant-derived medicines for human disease treatment have become a popular research area.
Computational Approaches in Drug Discovery, Development and Systems Pharmacology
Computational Approaches in Drug Discovery, Development and Systems Pharmacology provides detailed information on the use of computers in advancing pharmacology. Drug discovery and development is an expensive and time-consuming practice, and computer-assisted drug design (CADD) approaches are increasing in popularity in the pharmaceutical industry to accelerate the process. With the help of CADD, scientists can focus on the most capable compounds so that they can minimize the synthetic and biological testing pains. This book examines success stories of CADD in drug discovery, drug development and role of CADD in system pharmacology, additionally including a focus on the role of artificial in...
