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Trends in Neuroimmunology: cross-talk between brain-resident and peripheral immune cells in both health and disease
The functional anatomy of organisms is maintained by the coordination of different systems, that often rely on particular interactions between specialized cells and between macromolecules. The immune system works with the circulatory and the lymphatic systems to protect most of the organs. However, some organs are considered immune privileged due to the presence of highly selective and regulated barriers, such as the blood-brain barrier (BBB) within the brain. The BBB controls periphery-brain molecule exchange and prevents immune effector cells from entering the homeostatic brain. BBB-associated elements, such as endothelial cells, pericytes, astrocytes, and microglia, potentially can functi...
Mutagenesis
The complexity of problem understanding biochemical and molecular basis of healthy life, and eagerness to find simple solution necessitate evolution of technology like mutagenesis. The chapters of this book contain experiences of scientists working in the area of mutagenesis. It describes suitable experimental models (microorganism, plants or animals) for testing spontaneous and induced mutations which are useful for basic and translational research. It includes methods towards gene targeting, developing disease and pest resistant plants, creating temperature sensitive molecular machines, understanding mitochondrial mutagenesis, detecting anti-mutagens, improving genetic insight into impaired immunity and disease. It also describes mutagenesis induced by DNA damage. It has also provided advantage of in vitro transcription and translation to yield proteins with point mutations, deletions or insertions for studying stability, DNA-protein or protein-protein interaction. Trust, it will serve readers as valuable integrated resources emphasizing methods of mutagenesis, and understanding mechanism of variable penetrance or expressivity of mutations.
Current Affairs October 2017 eBook
Current Affairs October 2017 eBook is created by keeping the demands of recent pattern of various competitive exams in major view. It is brought to you by Jagranjosh.com. The topics for cover story and entire news section are selected on the basis of an analysis of general knowledge sections in all important exams including IAS, PCS, BANK, SSC, Insurance and others. And the time duration of topics covered in magazine includes all exam oriented current affairs of September 2017. It presents the comprehensive coverage of the events of current affairs which are chosen on the basis of the requirements of all important exams. It covers all exam oriented current affairs of September 2017 with all ...
Topics in Biomedical Gerontology
This book presents a collection of articles on various aspects of current research on aging. These include model systems, cellular, biochemical and molecular aspects of experimental aging research, as well as selected intervention studies on age-related diseases. Aging is a global challenge to human society. Children are always in a hurry to become adults, while adults produce offspring and add to the gene pool. However, after adulthood or the attainment of reproductive maturity, all physiological parameters of the living organism start to undergo the aging process. Old age sets in slowly but surely, and usually continues for a prolonged period. If vigor and vitality are the main advantages ...
Operation Bazooka: The True Story behind the Hunt for the Most Dreaded UP Gangster ǀ True crime account of Shriprakash Shukla’s encounter
Who could pump 112 bullets to kill a man in a posh Lucknow locality? Why did a criminal hang around prep schools in Lucknow? How did a phone call to the daughter of a government engineer blew the lid off the plan to assassinate the Chief Minister of Uttar Pradesh? And who can tell the story of Operation Bazooka better than the man who was a part of it! Police officer Rajesh Pandey was among the founding members of the UP STF (Special Task Force), created to nab Shriprakash Shukla – one of the most dreaded gangsters in Uttar Pradesh, The book gives a detailed account of the workings of the STF and how they nabbed the gangster. Read about the country’s first electronic surveillance unit developed by Pandey during the operation and how the police got the only photograph of the gangster available till date. Operation Bazooka is a no-holds-barred, bone-chilling true account of Shriprakash Shukla’s reign of terror and how the STF went after him.
Quarterly Current Affairs - July to September 2017 for Competitive Exams Vol 3
Quarterly Current Affairs - July to September 2017 for Competitive Exams is a unique handy magbook as it gives the complete update of the 3rd Quarter months of 2017. The book talks of all the recent developments in the field of Polity, Economics, Sience & Technology, Sports, Art & Culture etc. This book would prove to be an asset for all students aspiring for the different competitive exams. The book highlights the gist of the 3rd Quarter of 2017 through Game Changers, Causes & Effects, Quote & Unquote, etc.
Natural Molecules in Neuroprotection and Neurotoxicity
Natural Molecules in Neuroprotection and Neurotoxicity brings together research in the area of natural compounds and their dual effects of neuroprotection and neurotoxicity when interacting with brain cells. This book is organized into four sections that address molecular mechanism underlying neuroprotection and neurotoxicity, neuroprotection mediated by natural molecules, neurotoxicity induced by natural compounds and nanotechnology-related strategies utilized in neuroprotection. Written by well-known researchers all over the world, chapters provide an in-depth analysis of numerous molecules, such as algae, plant and fungus-derived molecules, and comprehensively discuss their mechanisms of ...
Models, Molecules and Mechanisms in Biogerontology
The book deals with basic cellular and molecular mechanisms associated with aging. It comprehensively describes the important genetic, epigenetic, biochemical and metabolic regulations during aging, as well as some important age-related diseases.The book is divided into four major sections for easy understanding. It takes the readers through the various aspects of aging in a story-like manner. Certain interventions for healthy aging such as dietary restriction, regular exercise and maintaining a balanced and peaceful life-style are also suggested by the experts. The book would be a companion for both beginners, as well as established researchers in the field. It would be useful for science education, research, clinical approach and policy making.
