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Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: insights into the way the blood-brain barrier actually works (Celebrating the centenary of Goldman’s experiments)
When Ehrlich discovered the first evidence of the blood-brain barrier in 1885, he probably did not perceive the Great Wall that remained hidden from consciousness inside the central nervous system. Ehrlich had observed that acidic vital dyes did not stain the brain if they were injected into the blood stream. A century ago (1913), Goldman showed that the injection of trypan blue in the cerebrospinal fluid stained only the brain, but not the other organs. For almost a century it was thought that the blood-brain barrier (BBB) consisted in a physical barrier, resulting from the restricted permeability of the cerebral endothelial cell layer, as they are joined by tight junctions. However, as sci...
Bachata and Dominican Identity / La bachata y la identidad dominicana
Bachata--a guitar-based romantic music that debuted in Santo Domingo's urban shantytowns in the 1960s--is today one of the hottest Latin genres. Still, fans and musicians have not forgotten the social stigma the genre carried for decades. This book interweaves bachata's history and development with the socio-political context of Dominican identity. The author argues that its early disfavor resulted from the political climate of its origins and ties between class and race, and proposes that its ultimate acceptance as a symbol of Dominican identity arose from its innovations, the growth of the lower class, and a devoted following among Dominican migrants. La bachata--una musica de guitarra que...
Atlas of the maturity stages of Mediterranean fishery resources
This atlas aims to present sound approaches to maturity sampling for a wide range of Mediterranean species – including bony fish, cartilaginous fish, both oviparous and viviparous, crustaceans and cephalopods – based on an accurate determination of the different maturity stages. It includes macroscopic photos of gonads belonging to the main species and, for some, a validation-based histological analysis.
DTM
None
Human Milk and Lactation
Human milk is uniquely tailored to meet infants’ specific nutritional requirements. However, it is more than just “milk”. This dynamic and bioactive fluid allows mother–infant signalling over lactation, guiding the infant in the developmental and physiological processes. It exerts protection and life-long biological effects, playing a crucial role in promoting healthy growth and optimal cognitive development. The latest scientific advances have provided insight into different components of human milk and their dynamic changes over time. However, the complexity of human milk composition and the synergistic mechanisms responsible for its beneficial health effects have not yet been unra...
Sainetes
Reimpresión del original, primera publicación en 1843.
Worldwide Regulations for Mycotoxins in Food and Feed in 2003
Since the discovery of the aflatoxins in the 1960s, mycotoxin regulations have been established in many countries, both to protect the consumer from the harmful effects of these toxins that may contaminate foodstuffs and to ensure fair practices in food trade. This publication updates developments in worldwide mycotoxin regulation as of December 2003, based on an international enquiry carried out in 2002/2003.
