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Focus on Malignant Pleural Mesothelioma Immunology and Immunotherapy
Malignant pleural mesothelioma (MPM) is a rare thoracic cancer that derives from the mesothelial cells of the pleura and is causally associated with exposure to asbestos. Because of its aggressiveness and resistance to therapies, MPM prognosis is extremely poor and the 5-year survival rate is approximately 10%. Despite its poor effectiveness, chemotherapy with cisplatin and pemetrexed has long remained the standard-of-care for upfront treatment with no second line therapy available. Recently, the approval of ipilimumab (anti-CTLA-4) plus nivolumab (anti-PD-1) for the first-line treatment of unresectable MPM has marked a significant milestone, in particular for the non-epithelioid MPM subtype...
Mucosal Immunology
Mucosal Immunology, now in its fourth edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. Most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes, making this subject an area of singular importance in the field of immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective, and excellent organization. It covers immune system topics, such as inductive and effector tissues and cells, and development and physiology of the mucosal barrier; diseases in the digestive system, respiratory tract, and genitourinary tract; and immunodeficiency. - The most comprehensive text on mucosal immunology from internationally recognized experts in the field - Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases - Contains nine new chapters and an expanded appendix
The Key to Rebecca
The Key to Rebecca is a gripping thriller set during the Second World War, from master storyteller and author of The Pillars of the Earth, Ken Follett. A Ruthless Spy 1942. Alex Wolff’s goal is Cairo. Following a relentless trek across the scorching Sahara, he arrives in the city with a copy of Daphne du Maurier’s Rebecca, a lethal blade and a trail of bodies in his wake. Known to his handlers as the ‘Sphinx’, Wolff is a Nazi spy with a brutal desire to succeed. A Failing Campaign The British campaign in North Africa hangs in the balance. Led by Rommel, the Germans are closing in and the Sphinx’s reports on British troop movements and strategic plans are giving them the edge. Intelligence officer Major William Vandam is tasked with hunting down the Sphinx before the British are defeated. A Deadly Chase Vandam enlists the help of courtesan Elene Fontana, who agrees to try and ensnare the spy in exchange for a better life in Palestine. Can they catch the master spy before he uncovers Cairo’s secrets and the campaign fails?
The Neurology of Religion
Examines what can be learnt about the brain mechanisms underlying religious practice from studying people with neurological disorders.
Was gibt es Neues in der Chirurgie? JB 2014
Der Jahresband 2014: Renommierte Chirurgen skizzieren fortlaufend die Entwicklung ihres Spezialgebietes, sichten aktuelle Literatur, werten Kongressberichte aus, spüren Trends auf und beschreiben anschaulich neueste Verfahren. Außerdem wird bei allen relevanten Themen darauf eingegangen, wie sich Komplikationen vermeiden lassen. Durch das übersichtliche Layout, die Fazit-Zusammenfassungen am Ende jedes Kapitels und die themenspezifischen Griffmarken ist das Werk in der Praxis handlich und lesefreundlich. Selbstverständlich sind auch in diesem Jahr wieder CME-Fragen dabei (Continous Medical Education das etablierte Pflichtweiterbildungssystem für Mediziner), mit denen wichtige Fortbildungspunkte zu erwerben sind.
