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Coronary Vasculature
Ischemic heart disease is the leading cause of morbidity and mortality in the developed world. The high metabolism and oxygen demand of the cardiac myocardium depends on both a high blood flow and a rich capillary density. For this reason, the growth of the coronary vasculature is vital, not only in early development, but also in the adult faced with various stresses. Novel technologies have enabled the discovery of the molecular mechanisms underlying the growth and assembly coronary vessels, and this volume covers the hierarchy of the coronary vasculature from its embryonic origins through its postnatal growth, adulthood, and senescence. Chapters address normal coronary development, coronar...
Moravia: Gem of the Czech Republic
Like many other European countries, the Czech Republic has a rich culture and history, which makes it a magnet for travelers to Eastern Europe. This book concentrates on the territory of Moravia, a part of the Czech Republic, often in the shadow of the capital city of Prague but which deserves attention and appreciation in its own right. After all, it is the place where the Great Moravian Empire was established and became the first major homeland of the Slavic people. The book brings a unique view of how this region is seen and understood from afar-the United States. The author writes, "The absence of a published focus on Moravia, one of the two main regions of the Czech Republic, was for me...
Assembly of the Vasculature and Its Regulation
The overall scope of this new series will be to evolve an understanding of the genetic basis of (1) how early mesoderm commits to cells of a heart lineage that progressively and irreversibly assemble into a segmented, primary heart tube that can be remodeled into a four-chambered organ, and (2) how blood vessels are derived and assembled both in the heart and in the body. Our central aim is to establish a four-dimensional, spatiotemporal foundation for the heart and blood vessels that can be genetically dissected for function and mechanism. Since Robert DeHaan's seminal chapter "Morphogenesis of the Vertebrate Heart" published in Organogenesis (Holt Rinehart & Winston, NY) in 1965, there hav...
Formation of the Heart and its Regulation
The `Formation of the Heart and its Regulation` reviews in considerable detail the major events in heart development and their control via genes, cell-cell interactions, growth factors and other contributing elements. In addition, there is an extensive and useful overview of the field of heart development taken as a whole. The book will appeal to all students and researchers working on cardiovascular development and to pediatric cardiologists.
Aging and Cell Structure
Approaching any task on aging brings a flood of images that are a personal repetition of what has been one of the greatest and most persistent concerns of mankind. Even restricting time to the past decade or so and approaching only the biomedical sciences, one still encounters a flood of information in this relatively young research area. The ories and ideas abound as though each researcher provides one of his own. This might well be expected; aging is an exceedingly complicated series of crossroads involving trails and even superhighways. Each specialist has a peephole (society, body, organ, tissue, cell, or-especially in modern biology-cellular organelles, macromolecules, and even molecule...
Czech Immigrants and the Sokol Movement
"Czech Immigrants and the Sokol Movement" is about the people of the Czech lands who settled in the USA, bringing their ideals and culture, and contributing in many ways to American life. They left their homeland because they were denied independence under Austrian rule during the late 19th and early 20th centuries. Their culture included the Sokol movement, a philosophy of fitness through gymnastics (a sound mind in a sound body), which stressed discipline, morality, brotherhood, and equality. The movement was so strong that it helped spark the Czech Legions, an army consisting of men who left the Austrian army in order to fight on the side of the allies during World War I. Their legacy was a major factor that rallied support for the establishment of Czechoslovakia in 1918. This is the story of a determined people who sacrificed, endured, and contributed to the American way of life, especially by their love of country and freedom. The book documents the role of Sokol clubs in facilitating the Czech culture in America by contributing to fitness through gymnastics, as well as the arts.
