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Repetitive Structures in Biological Sequences: Algorithms and Applications
Repetitive structures in biological sequences are emerging as an active focus of research and the unifying concept of "repeatome" (the ensemble of knowledge associated with repeating structures in genomic/proteomic sequences) has been recently proposed in order to highlight several converging trends. One main trend is the ongoing discovery that genomic repetitions are linked to many biological significant events and functions. Diseases (e.g. Huntington's disease) have been causally linked with abnormal expansion of certain repeating sequences in the human genome. Deletions or multiple copy duplications of genes (Copy Number Variations) are important in the aetiology of cancer, Alzheimer, and...
Bioinformatics of Non-Coding RNAs with Applications to Biomedicine: Recent Advances and Open Challenges
The recent discovery of small and long non-coding RNAs (ncRNAs) has represented a major breakthrough in the life sciences. These molecules add a new layer of complexity to biological processes and pathways by revealing a sophisticated and dynamic interconnected system whose structure is just beginning to be uncovered. Genetic and epigenetic aberrations affecting ncRNA gene sequences and their expression have been linked to a variety of pathological conditions, including cancer, cardiovascular and neurological diseases. Latest advances in the development of high throughput analysis techniques may help to shed light on the complex regulatory mechanisms in which ncRNA molecules are involved. Bi...
Biological Knowledge Discovery Handbook
The first comprehensive overview of preprocessing, mining, and postprocessing of biological data Molecular biology is undergoing exponential growth in both the volume and complexity of biological data and knowledge discovery offers the capacity to automate complex search and data analysis tasks. This book presents a vast overview of the most recent developments on techniques and approaches in the field of biological knowledge discovery and data mining (KDD) providing in-depth fundamental and technical field information on the most important topics encountered. Written by top experts, Biological Knowledge Discovery Handbook: Preprocessing, Mining, and Postprocessing of Biological Data covers ...
Intelligent Computing Methodologies
This book – in conjunction with the volumes LNCS 8588 and LNBI 8590 – constitutes the refereed proceedings of the 10th International Conference on Intelligent Computing, ICIC 2014, held in Taiyuan, China, in August 2014. The 85 papers of this volume were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections such as soft computing; artificial bee colony algorithms; unsupervised learning; kernel methods and supporting vector machines; machine learning; fuzzy theory and algorithms; image processing; intelligent computing in computer vision; intelligent computing in communication networks; intelligent image/document retrievals; intelligent da...
Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics
This book constitutes the refereed proceedings of the 9th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2011, held in Torino, Italy, in April 2011 co-located with the Evo* 2011 events. The 12 revised full papers presented together with 7 poster papers were carefully reviewed and selected from numerous submissions. All papers included topics of interest such as biomarker discovery, cell simulation and modeling, ecological modeling, fluxomics, gene networks, biotechnology, metabolomics, microarray analysis, phylogenetics, protein interactions, proteomics, sequence analysis and alignment, and systems biology.
Computational Intelligence Methods for Bioinformatics and Biostatistics
This book constitutes revised selected papers from the 16th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2019, which was held in Bergamo, Italy, during September 4-6, 2019. The 28 full papers presented in this volume were carefully reviewed and selected from 55 submissions. The papers are grouped in topical sections as follows: Computational Intelligence Methods for Bioinformatics and Biostatistics; Algebraic and Computational Methods for the Study of RNA Behaviour; Intelligence methods for molecular characterization medicine; Machine Learning in Healthcare Informatics and Medical Biology; Modeling and Simulation Methods for Computational Biology and Systems Medicine.
Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics
The ?eld of bioinformatics has two main objectives: the creation and main- nance of biological databases, and the discovery of knowledge from life sciences datainordertounravelthemysteriesofbiologicalfunction,leadingtonewdrugs andtherapiesforhumandisease. Life sciencesdatacomeinthe formofbiological sequences, structures, pathways, or literature. One major aspect of discovering biological knowledge is to search, predict, or model speci'c information in a given dataset in order to generate new interesting knowledge. Computer science methods such as evolutionary computation, machine learning, and data mining all have a great deal to o'er the ?eld of bioinformatics. The goal of the 8th - ropean ...
Practical Applications of Computational Biology and Bioinformatics, 16th International Conference (PACBB 2022)
This book is suitable for researchers and practitioners in biology, medicine and health sciences and bioinformatics. The success of bioinformatics and computational biology in recent years has been driven by research through computational tools and techniques that are essential for data analysis in modern biology and medicine. Systems biology is a related research area that has been replacing the reductionist view that dominated biology research in the last decades, requiring the coordinated efforts of biological researchers with those related to data analysis, mathematical modelling, computer simulation and optimization. The accumulation and exploitation of large-scale databases prompt new ...
Complex Networks & Their Applications IX
This book highlights cutting-edge research in the field of network science, offering scientists, researchers, students and practitioners a unique update on the latest advances in theory and a multitude of applications. It presents the peer-reviewed proceedings of the IX International Conference on Complex Networks and their Applications (COMPLEX NETWORKS 2020). The carefully selected papers cover a wide range of theoretical topics such as network models and measures; community structure, network dynamics; diffusion, epidemics and spreading processes; resilience and control as well as all the main network applications, including social and political networks; networks in finance and economics; biological and neuroscience networks and technological networks.
