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Inhibitory Function in Auditory Processing
There seems little doubt that from the earliest evolutionary beginnings, inhibition has been a fundamental feature of neuronal circuits - even the simplest life forms sense and interact with their environment, orienting or approaching positive stimuli while avoiding aversive stimuli. This requires internal signals that both drive and suppress behavior. Traditional descriptions of inhibition sometimes limit its role to the suppression of action potential generation. This view fails to capture the vast breadth of inhibitory function now known to exist in neural circuits. A modern perspective on inhibitory signaling comprises a multitude of mechanisms. For example, inhibition can act via a shun...
Hormone Action and Signal Transduction in Endocrine Physiology and Disease
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Astrocytic-neuronal-astrocytic Pathway Selection for Formation and Degradation of Glutamate/GABA
Endocrinological research early recognized the importance of intercellular interactions and realized the importance of glutamatergic and GABAergic signaling. In turn this signalling depends on elaborate interactions between astrocytes and neurons, without which neurons would be unable to produce, reuse and metabolize transmitter glutamate and GABA. Details of these subjects are described in this Research Topic by key investigators in this field. It focuses on the intricate and extremely swift pathway producing these amino acid transmitters from glucose in brain but also discusses difficulties in determining expression of some of the necessary genes in astrocytes and related processes in pancreatic islets. However, it does not discuss how closely associated astrocytes and neurons are anatomically, enabling these interactions. This is elegantly shown in this cover image, kindly provided by Professor Andreas Reichenbach (University of Leipzig, Germany).
Ionotropic Glutamate Receptors Trafficking in Health and Disease
The knowledge about the properties and importance of ionotropic glutamate receptor trafficking is ever increasing. Importantly, the pace of the progress has been accelerated in recent years. Here, our contributors provide a) reviews on specific topics that present an up-to-date overview of the field, as well as b) original articles with the relevant new findings.
Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B
Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B, a new volume of Advances in Pharmacology, presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years, which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development. - Contributions from the best authors in the field - An essential resource for pharmacologists, immunologists, and biochemists
Plasticity and Signal Representation in the Auditory System
The symposium that has provided the basis for this book, "Plasticity of the Central Auditory System and Processing of Complex Acoustic Signals" was held in Prague on July 7-10, 2003. This is the fourth in a series of seminal meetings summarizing the state of development of auditory system neuroscience that has been organized in that great world city. Books that have resulted from these meetings represent important benchmarks for auditory neuroscience over the past 25 years. A 1980 meeting, "Neuronal Mechanisms of Hearing" hosted the most distinguished hearing researchers focusing on underlying brain processes from this era. It resulted in a highly influential and widely subscribed and cited ...
