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This textbook presents the latest information on pharmacogenetics and pharmacogenomics for students, professionals and researchers.
This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as:• tree structured data, interval trees, and time-oriented medical data and their use• On Line Application Processing (OLAP), an old database idea that is only recently coming of age and finding surprising importance in bio...
This book constitutes the refereed proceedings of the 19th International Conference on Logic Programming, ICLP 2003, held in Mumbai, India in December 2003. The 23 revised full papers and 19 poster papers presented together with 5 invited full contributions and abstracts of 4 invited contributions were carefully reviewed and selected from 81 submissions. All current issues in logic programming are addressed.
Constraint programming is a powerful paradigm for solving combinatorial search problems that draws on a wide range of techniques from artificial intelligence, computer science, databases, programming languages, and operations research. Constraint programming is currently applied with success to many domains, such as scheduling, planning, vehicle routing, configuration, networks, and bioinformatics.The aim of this handbook is to capture the full breadth and depth of the constraint programming field and to be encyclopedic in its scope and coverage. While there are several excellent books on constraint programming, such books necessarily focus on the main notions and techniques and cannot cover...
The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical infor...
In the past several years, DNA microarray technology has attracted tremendous interest in both the scientific community and in industry. With its ability to simultaneously measure the activity and interactions of thousands of genes, this modern technology promises unprecedented new insights into mechanisms of living systems. Currently, the primary applications of microarrays include gene discovery, disease diagnosis and prognosis, drug discovery (pharmacogenomics), and toxicological research (toxicogenomics). Typical scientific tasks addressed by microarray experiments include the identification of coexpressed genes, discovery of sample or gene groups with similar expression patterns, identi...
Proceedings of the Tenth Course of the International School of Pure and Applied Biostructure (Erice, Italy, June 1989). Knowledge of protein structure and of design and manufacture methods has made it possible to produce proteins of any desired sequence, but progress is limited by inability to predi
The theme of Medinfo2007 is “Building Sustainable Health Systems”. Particular foci are health challenges for the developing and developed world, the social and political context of healthcare, safe and effective healthcare, and the difficult task of building and maintaining complex health information systems. Sustainable health information systems are those that can meet today’s needs without compromising the needs of future generations. To build a global knowledge society, there needs to be an increased cooperation between science and technology and access to high-quality knowledge and information. The papers presented are refereed and from all over the world. They reflect the breadth and depth of the field of biomedical and health informatics, covering topics such as; health information systems, knowledge and data management, education, standards, consumer health and human factors, emerging technologies, sustainability, organizational and economic issues, genomics, and image and signal processing. As this volume carries such a wide collection, it will be of great interest to anyone engaged in biomedical and health informatics research and application.
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