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Experts estimate that as many as 98,000 people die in any given year from medical errors that occur in hospitals. That's more than die from motor vehicle accidents, breast cancer, or AIDSâ€"three causes that receive far more public attention. Indeed, more people die annually from medication errors than from workplace injuries. Add the financial cost to the human tragedy, and medical error easily rises to the top ranks of urgent, widespread public problems. To Err Is Human breaks the silence that has surrounded medical errors and their consequenceâ€"but not by pointing fingers at caring health care professionals who make honest mistakes. After all, to err is human. Instead, this book se...
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Plants have evolved with a complex array of signaling molecules to facilitate their growth and development and their interactions with the environment. A vast number of different peptide molecules form an important but until recently often overlooked component amongst these signaling molecules. Plant peptide signals are involved in regulating meristem growth and organogenesis, modulating plant growth and homeostatic responses. They also have important roles as signals of imminent danger or pathogen attack. This volume focuses on the roles of various peptide signaling molecules in development, defence and homeostasis. As it is likely that further plant peptide signaling molecules remain to be discovered, the last section takes a practical look at methods to identify new peptides and characterise their functions.
This book examines in detail the current treatment options for first-line, relapsed, and refractory Hodgkin lymphoma and the management appropriate in special clinical circumstances, including in the elderly, pregnant women, and those with lymphocyte-predominant disease. Careful attention is devoted to the emerging individually tailored treatment strategies that are especially appealing given their potential to reduce early and late treatment side effects in this generally young patient population. In addition, clear guidance is provided on the management of Hodgkin survivors. Other topics addressed include epidemiology, pathogenesis, the role of the microenvironment, initial clinical evaluation, imaging diagnosis, use of staging systems, and prognostic factors. The second edition of Hodgkin Lymphoma: A Comprehensive Overview has been revised and updated by the key opinion leaders to reflect recent progress in the field. It will be of great value to hematologists, oncologists, and all others with an interest in Hodgkin lymphoma.
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This book is a comprehensive guide that will help medical professionals – pediatric oncologists, nurses, pediatricians, family practitioners, internists, radiation oncologists, surgeons – to understand and manage the long-term effects of treatment for childhood and adolescent cancer. The consequences of treatment are described for each organ system, with explanation of pathophysiology, clinical manifestations, detection and screening and management. Disease- and organ-based algorithms of care and tables designed to facilitate the assessment of late effects are highlights of the book and will assist in the provision of hands-on care that is up to date and geared to clinical need. Among the other topics addressed are stem cell transplantation, psychological care, legal issues, transition to adulthood and methodological issues in the study of survivorship care.