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SPIRO COMPOUNDS A comprehensive treatment of the latest research in, and applications of, spiro compounds Spiro Compounds: Synthesis and Applications combines discussions of the latest advances in spiro compound research with the most cutting-edge, real-world applications of that knowledge. This book provides in-depth coverage of the history, significance, properties, synthetic methods, and applications of spiro compounds. As interest in spiro compounds grows due to their unique conformational features and their structural implications on biological systems, Spiro Compounds delivers fulsome treatments of advances in spiro compound synthesis (including stereoselective synthesis) methodologies...
This book provides a comprehensive overview for postgraduate students, academic staff and industry professionals working on spiro compounds. This book covers a wide range of topics regarding these compounds, such as nomenclature, synthesis strategies, and their applications. The book includes modern, up-to-date information, dating from 2000 to the present. This extensive collection will inspire both academics and industrialists to contribute to future advances in this field.
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This volume is devoted to compounds in which the spiro centre is part of a pyranoid or furanoid or an iminosugar ring. The chapters contributed deal with methodological peculiarities of syntheses of natural and artificial sugar derived spirocycles as well as their biological applications and other utilities including marketed drugs. Carbohydrates are ubiquitous molecules in nature and participate in a vast number of biological interactions. Especially their conjugates with practically all kinds of primary and secondary metabolic small molecules (and also biomacromolecules) representing valuable tools for glycobiology research and also lead compounds for drug discovery. While monosaccharides per se appear as heterocycles, their natural conjugates frequently exhibit spiro(hetero)cyclic derivatives, in many cases of high therapeutical relevance. As a consequence, the field of carbohydrate-spiro-heterocycles attracts intense interest from both chemical and biomedical aspects therefore this volume will be of interest for synthetic and medicinal chemists and (glyco)biologists, as well as researchers involved in various biomedical fields.
Collaborative Insights provides new perspectives informed by interdisciplinary thinking on musical care throughout the life course. In this book, volume editors Katie Rose M. Sanfilippo and Neta Spiro define musical care as the role that music - music listening as well as music-making - plays in supporting any aspect of people's developmental or health needs, for example physical and mental health, cognitive and behavioural development, and interpersonal relationships. Musical care is relevant to several types of music, approach, and setting, and through the introduction of that new term musical care, the authors prioritise the element of care that is shared among these otherwise diverse con...
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This book addresses the synthesis of photosensitizers, the main emphasis being on the new methods of synthesis such as microwave, sonochemistry and the use of ionic liquids. It also addresses the photochemistry and photophysics of the photosensitizers alone and in combination with nanoparticles, the use of the photosensitizers in environmental control, safety and medicine. It discusses the common structures of the photosensitizers which are beneficial to these applications.
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This third volume in the successful 'Drug Discovery in Infectious Diseases' series is the first to deal with drug discovery in helminthic infections in human and animals. The result is a broad overview of different drug target evaluation methods, including specific examples of successful drug development against helminthes, and with a whole section devoted to vaccine development. With its well-balanced mix of high-profile contributors from academia and industry, this handbook and reference will appeal to a wide audience, including parasitologists, pharmaceutical industry, epidemiologists, and veterinary scientists.