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At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological mechanisms as potential drug targets and enhance the creation of new drug therapies. This book comprises the proceedings of the Uehara Memorial Foundation Symposium 2011, which focused on the most recent advances in chembiomolecular science made by leading experts in the field. The book is divided into three main topics. The first is the chemical approach to understanding complex biological systems on a molecular level using chem...
Since the inelastic scattering of light was predicted nearly 100 years ago, Raman spectroscopy has become a mainstay of characterization techniques, with applications in a vast array of fields from chemistry to materials science and nanotechnology, from forensics to geology and art. More recently, it has found usage in the life sciences, and this book hereby outlines the state-of-the-art advances in applications of Raman spectroscopy to human health and biomedicine. It covers a wide range of human health science including medicine (especially cancer), physiology, biological molecules, pharmaceutical science, cells, viruses, microorganisms, and food science. Another highlight is that it describes recent progress on various Raman techniques such as surface-enhanced Raman scattering, tip-enhanced Raman scattering, non-linear Raman spectroscopy, Raman microscopy, and Raman imaging. Novel spectral analysis methods such as chemometrics are also prominently discussed.
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예쁜꼬마선충은 토양에서 서식하며 투명한 몸을 가진 1mm 크기의 아주 작은 벌레다. 대중에게 생소한 이 벌레는 생물학계의 스타이자 지구상에서 인간이 가장 ‘잘’ 이해하고 있는 다세포 생명체다. 어느 한 곳 인간과 닮은 데가 없는 이 벌레는 놀랍게도 유전자의 절반 이상이 인간의 유전자와 유사하고 그 기능 역시 많은 부분 유사하다. 이런 선충의 특징을 자크 모노의 표현을 빌려 표현하면, ‘벌레에게 진실인 것은 인간에게도 진실이다’라 할 수 있다. 현대 생물학은 이와 같은 기치 아래에서 예쁜꼬마선충을 통해 인간과 생명의 보편성을 이해하기 위한 여정 중에 있다. <벌레의 마음>은 이러한 최신 현대 생물학의 여정을 대중들과 함께 나누고 소통하고자 하는 예쁜꼬마선충 과학자 5인의 진지한 고민을 담고 있다.
The life of proteins starts and ends as amino acids. In addition to the primary function as protein building blocks, amino acids serve multiple other purposes to make a plant's life worth living. This is true especially for the amino acids of the glutamate family, namely glutamate (Glu), glutamine (Gln), proline (Pro) and arginine (Arg), as well as the product of Glu decarboxylation, ?-aminobutyric acid (GABA). Synthesis, accumulation, interconversion and degradation of these five compounds contribute in many ways to the regulation of plant development and to responses to environmental challenges. Glu and Gln hold key positions as entry points and master regulators of nitrogen metabolism in ...
Stimulated Raman Scattering Microscopy: Techniques and Applications describes innovations in instrumentation, data science, chemical probe development, and various applications enabled by a state-of-the-art stimulated Raman scattering (SRS) microscope. Beginning by introducing the history of SRS, this book is composed of seven parts in depth including instrumentation strategies that have pushed the physical limits of SRS microscopy, vibrational probes (which increased the SRS imaging functionality), data science methods, and recent efforts in miniaturization. This rapidly growing field needs a comprehensive resource that brings together the current knowledge on the topic, and this book does ...
This publication brings together information on all aspects of OPLL - epidemiology, etiology, diagnosis, and treatment. It contains contributions by Japanese researchers and surgeons, including members of the Ministry of Health and Welfare Investigation Committee, and by American surgeons with expertise in the field. Until now, little has been published on the subject in English. This collection of reports is amply augmented with illustrations.