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Photoproteins in Bioanalysis
The use of light-emitting proteins for the detection of biomolecules provides fast and sensitive methods which overcome the disadvantages of radioactive labels and the high cost of fluorescent dyes. This reference work summarizes modern advanced techniques and their applications and includes practical examples of assays based on photoproteins. The book presents contemporary key topics like luminescent marine organisms, DNA probes, reporter gene assays and photoproteins, ratiometric sensing, use of photoproteins for in vivo functional imaging and luminescent proteins in binding assays, to name just a few, and is complemented by recent advances in instrumentation. Includes an introductory chapter by 2008 Chemistry Nobel laureate Osamu Shimomura.
Organumics: An Epigenetic Re-Framing of Consciousness, Life, and Evolution
Where does consciousness fit into biology? How did life evolve? What makes us human? These are just a few of the deep and universal questions that the new science and philosophy of epigenetics may be able to answer. Epigenetics ("above and beyond genetics") is an exciting new field, but it remains relatively unknown, even as genetics has been saturating scientific news since the early 1990s. Whether it was through the Human Genome Project, the heritability of a disease, or DNA ancestry testing, most people have likely heard of genetics. But, despite its popularity, very few truly understand the scope of genetics or what in fact constitutes a gene. Genetics is often thought of as the study of...
Bioinspired Nanomaterials
Biological synthesis employing microorganisms, fungi or plants is an alternative method to produce nanoparticles in low-cost and eco-friendly ways. The book covers the synthesis of metal nanoparticles, metal oxide nanostructures and nanocomposite materials, as well as the stability and characterization of bioinspired nanomaterials. Applications include optical and electrochemical sensors, packaging, SERS and drug delivery processes. Keywords: Bioinspired Nanomaterials, Metal Nanoparticles, Metal Oxide Nanostructures, Nanocomposite Materials, Microbicidal Activity, Drug Delivery, Packaging Applications, SERS Applications, Fluorescent Biosensing, Quantum Dots. Bio-Imaging, Electrochemical Sensors.
Luminescence Biotechnology
The dangers and drawbacks inherent in radioactivity-based methods along with a demonstrated and dramatic increase in sensitivity have precipitated a major shift towards luminescence measurements and visualization techniques. Their use has now spread even to traditional clinical environments, and their applications have grown from clinical assays to
Fluorescence Sensors and Biosensors
Fluorescence-based sensing is a significant technique used in prominent fields such as fluorescence-activated cell sorting, DNA sequencing, high-throughput screening, and clinical diagnostics. Fluorescence Sensors and Biosensors emphasizes the most recent developments and emerging technologies with the broadest impacts. The text begins wi
Sepsis
Sepsis is the major cause of death in non-cardiologic intensive care units around the world. Every year, billions of dollars are consumed in the treatment of sepsis and in research to understand its complex pathophysiology and therefore obtain future therapeutic opportunities. Despite the efforts of the scientists and medical practitioners, the mortality rates are still high and the incidence of sepsis is increasing. In this book we provide an update on several aspects of sepsis. Starting from the history of the disease and finishing with treatment of sepsis-associated organ dysfunctions, this book offers a wide scope of well-written and complete reviews concerning pathophysiological and therapeutic characteristics of sepsis. We hope that the work of the authors will provide a significant forum of discussion on the topic, and increase the awareness of the healthcare team regarding the important aspects of early recognition and treatment of this severe condition.
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Bioluminescence And Chemiluminescence: Chemistry, Biology And Applications
In life science, bioluminescence and chemiluminescence have become a vital tool for laboratory analysis and biomedical imaging both in academic research and industrial product development. The latest advances in this exciting field, from fundamental research to cutting-edge applications, are explored in this most recent volume of the biannual symposium series, the Proceedings of the 14th International Symposium on Bioluminescence and Chemiluminescence.The volume highlights advances in fundamental knowledge about the origins and mechanisms of naturally occurring luminescence, including luciferases from firefly, beetle, marine, bacterial and fungal sources. Developments in instrumentation are presented, together with a wide variety of optical imaging applications for light-emitting gene expressions in optical imaging, such as imaging of gene expression and protein folding in cells, tissues and live animals. In particular, the various contributors describe in detail the use of light-emitting bacteria and viruses for the detection and therapy of tumors, as was highlighted in the symposium.
Gut-brain Connection, Myth Or Reality?: Role Of The Microbiome In Health And Diseases
In this book the recent advancements in understanding the gut-brain interaction as well as gut microbiome and how this interaction plays a vital role in human health and disease are discussed. Each chapter gives an analysis of questions, research directions, and methods within the field of gut-brain axis. The readers will benefit from the latest knowledge about our understanding about how gut-brain axis and modulation of gut microbiome determines predisposition to neurological disorders. The multidisciplinary book is essential reading for anyone interested in the field of gut-brain axis and gut microbiome: from undergraduates to graduate students as well as scientists and physicians having an interest in the new exciting field of gut microbiome and its relationship with brain function.
