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Elastomeric proteins are ubiquitous in nature, where they have evolved precise structures and properties that are necessary to perform specific biological roles and functions. This book emphasizes the impact of amino acid sequence on modulating protein structure, properties, and function. Examples include conformational ensemble dynamics, environmental responsiveness, self-assembly, physico-mechanical properties, morphology, and properties tailored for biomedical applications. This foundational framework is not only critical to advance scientific understanding and knowledge on elastomeric proteins but also enables the conceptualization, rational design, and development of biosynthetic elastomers and their analogous polypeptides for a variety of applications. Edited and contributed by pioneering researchers in the field, the book provides a timely overview of the materials, along with the synthesis techniques, the unique characteristics of elastomeric proteins, and biomedical and industrial applications. The book will provide a reference for graduate students and researchers interested in designing biomimetic proteins tailored for various functions.
This book features selected papers presented at the 20th International Conference on Near Infrared Spectroscopy. It discusses the latest progress in the field of near infrared spectroscopy from around the globe, including the advances in instrumentation, spectral interpretation and Chemometrics. In addition, it presents potential trends for near infrared spectroscopy in the next decade and highlights developments in process analytical technology, chemical imaging and deep learning. It can be used as a reference book for researchers and application personnel engaged in spectroscopy technology, Chemometrics, analytical instruments, on-site rapid or on-line analysis, process control and other fields. It will also be useful for undergraduates and postgraduates studying these topics.
This book aims to comprehensively summarize the current research status of nanomaterials and cell biology. It highlights the biological effects and biomedical applications of nanomaterials for specific diseases, bone tissue engineering, and skeletal muscle regeneration. It also provides the details of the biomedical applications of nucleic acid nanomaterials in drug delivery carriers, antimicrobial therapy, vaccine, and neurodegenerative diseases. Therefore, this book renders the audience a better understanding of nanomaterials along with the diverse applications in the cell biology field from recent works to perspectives.
Photodynamic therapy (PDT) utilizes photosensitizers (PS) together with irradiating light of specific wavelength interacting with oxygen to generate cytotoxic reactive oxygen species, in particular singlet oxygen, which has been approved for the clinical treatments of several malignant and non-malignant pathologies. Most recently, enhanced PDT was successfully achieved by using new light sources (i.e., light-emitting diode), novel functional nano-PSs, oxygen supply and synergistic therapy. In addition, PDT was widely used in the fields of antibacterial, antimicrobial and antibiofilm activities. The aim of this book is to highlight innovations in the fundamental mechanisms of enhanced PDT for clinical applications, and 20 papers published in the Journal of Innovative Optical Health Sciences during 2020-2023 were selected.
At present, the intensification of global climate and environmental change has led to frequent occurrence of natural hazards. Various types of natural hazards always overlap and interact, or occur in a chain reaction, with a wide range of impacts and a long period of time, resulting in serious disaster losses. Typically, major earthquakes and geological hazards, extreme meteorological hazards, large-scale floods and droughts, marine disasters, and forest and grassland fires, as well as their compound and chained hazards are among the key factors affecting human life safety and world economic development. To better our understanding of disaster prevention, mitigation, and relief, it is thus p...
Recent developments of experimental techniques in cellular and molecular biology have made it possible to understand the molecular biology of male gametogenesis in greater detail. This book focuses on the description of specialized proteins, which are dominantly and/or specifically expressed in germ cells and localized in spermatozoa. There is an urgent need to classify proteins of spermatogenic cells with a view of their functions, and their applications in the regulation of fertility and in understanding infertility. The understanding of structural properties of male germ cell specific proteins can offer vulnerable points for targeted intervention in testis without generalized effects on stages of spermatogenesis. Besides targeted action in male germ cells, sperm specific proteins and polypeptides may also offer potential application in the development of a contraceptive vaccine.
**Selected for Doody's Core Titles® 2024 in Clinical Genetics** Human Reproductive and Prenatal Genetics, Second Edition provides application-driven coverage of key topics in human reproductive and prenatal genetics, including genetic control underlying the development of the reproductive tracts and gametogenesis, the genetics of fertilization and implantation, the genetic basis of female and male infertility, as well as genetic and epigenetic aspects of assisted reproduction. Also examined are the genetics and epigenetics of the placenta in normal and abnormal pregnancy, preimplantation genetic diagnosis and screening, and cutting-edge advances in noninvasive prenatal screening, prenatal g...
One of the current research lines in analytical chemistry is the design and utilization of novel materials with higher selectivity and improved analytical performance in various steps of chemical analysis. In this sense, Metal–Organic Frameworks (MOFs) have attracted attention as a potential alternative to current commercially available materials. MOFs present an interesting set of properties, such as diverse structural topologies, modifiable pore size, high porosity, tuneable surface area, diverse composition, and versatile functionality. This book covers multipurpose usage MOFs in sample preparation, integration, and detection stages of analytical chemistry. Along with the application of MOFs in green analytical methodologies. It will serve as a reference book for researchers, scientists and engineers who are interested in developing new materials as well as researchers who are interested in new application development.