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Recent Advances in the Molecular Genetics of Glioma
Gliomas are central nervous tumours with a glial cell of origin, such as neural stem cells, astrocytes and oligodendrocytes. They usually occur in the brain (supratentorial, infratentorial, brainstem) but occasionally originate in the spine. Gliomas may be benign or malignant, comprise of various histopathological subtypes and WHO grades (I-IV). Despite having a low incidence rate of around 3.19 per 100,000 (in the US) and a median age of 64 years for a first diagnosis, gliomas account for 80% of malignant brain tumours, and are most often fatal; they are the leading cause of cancer-related death among males from the ages of 0-39 and in females aged 0-19.
Head & Neck
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Genome Research
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Drugs During Pregnancy and Lactation
The care of pregnant women presents one of the paradoxes of modern medicine. Women usually require little medical intervention during an (uneventful) pregnancy. Conversely, those at high risk of damage to their own health or that of their unborn require the help of appropriate medicinal technology, including drugs. Accordingly, there are two classes of pregnant women, the larger group requires support but not much intervention, while the other needs the full range of diagnostic and therapeutic measures applied in any other branch of medicine. This book presents the current state of knowledge about drugs in pregnancy. In each chapter information is presented separately for two different aspects of the problem seeking a drug appropriate for prescription during pregnancy, and assessing the risk of a drug when exposure has already taken place. Practising clinicians who prescribe medicinal products to women who are, or who may become, pregnant, will find this volume an invaluable reference.
AACR 2016: Abstracts 1-2696
The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
