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Dr. Jose Luis Subiza is the founder and CEO of Inmunotek SL. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Translational Neuroimmunology: Multiple Sclerosis provides an update on bench to bedside studies on Multiple Sclerosis as an autoimmune disease. Divided into twelve chapters, the book begins with an in-depth introduction to the neuroimmunology and immunopathology of multiple sclerosis. Sections also provide content on genetics and epigenetics, the microbiome, diagnosis, and treatment of multiple sclerosis. Finally, various precision treatments are covered. All information is presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research. - Provides an introduction on multiple sclerosis ...
Using the concept of "plasticity," or the brain’s ability to change through growth and reorganization, as a theoretical framework, this book argues that encouraging an exploration of the self better establishes emotional value in the composition classroom. This book explores recent evidence from studies in modern neuroscience to provide biological correlations between current and developing theory and pedagogy in Composition Studies. Starting with the concept of self, each subsequent chapter builds a neurobiological understanding of how emotional value, intrinsic motivation, creativity, and happiness are constructed and felt. This material exploration shows how these factors can maintain m...
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Conventional CD8+ and CD4+ T cells recognize antigens, presented by antigen-presenting cells in the form of short peptides loaded onto major histocompatibility complex (MHC) class I and class II molecules, through their T cell receptor (TCR). Somatic gene rearrangement of the TCR locus and randomization of TCR hyper-variable regions generate the marked diversity of TCRs. Once assembled, the heterodimeric TCR confers specificity to naïve T cells. The naïve T cell repertoire of an individual is established by selection processes in the thymus and cannot be broadened upon antigen recognition by additional somatic mutations. In humans, the estimated number of distinct TCRs in the naïve T cell...
"The texts in this volume represent the current theory, research and practice on the use of gel materials for treatment processes in the conservation of objects of art and surfaces in the built environment. The range of gels featured includes those drawn from the biological, cosmetic and food industries, as well as emerging products created specifically for conservation purposes"--Website.