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The concept of multipotent mesenchymal stromal cells (MSCs) arose from the work of A.J. Friedenstein and coworkers in which the authors observed that culturing human bone marrow (BM) cell suspensions, in plastic dishes, lead to isolation of proliferating adhered colonies of fribroblastoid cells able to differentiate into chondrocytes or osteoblasts, in vitro and in vivo. Authors firstly described these cells as colony forming units of fibroblastoid cells (CFU-Fs) referring to their ability to form large colonies on plastic surfaces. The acronymous “MSC” became popular after the work of A.I. Caplan et al in 1991 where the authors proposed that in adult BM, a population of stem cells could...
Mesenchymal stem cells (MSCs), a type of adult stem cells, have attracted the attention of scientists and physicians alike due to their unique biological properties and potential for disease treatment. As stem cell research is complex and progressing rapidly, it is important that the experts in this field share their views and perspectives. This book, co-edited by leading global researchers, is divided into three major sections and covers a broad range of topics concerning MSCs during their transition from benchside to bedside. The book is intended for researchers and clinicians in the field of stem cells. Dr. Robert Chunhua Zhao, MD. Ph.D is Cheung Kong Professor of Stem Cell Biology, Professor of Cell Biology at the Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, China Director of Center for Tissue Engineering, PUMC Chief scientist of 973 program Regional Editor of Stem Cells and Development.
Dr. Bourin works in a biotechnology company that develops a production process of ASC for clinical uses. Dr. Gimble is a co-founder, co-owner, and Chief Scientific Officer at Obatala Sciences and LaCell, biotechnology companies focused on the clinical translation of adipose-derived cells and tissues. The other Guest Editors declare no competing interests with regard to the Research Topic subject.
March 21-22, 2019 , Rome, Italy Key Topics : Cell Therapy,Gene Therapy,Stem Cell Therapies,Cell Culture and Bioprocessing,Viral Gene Therapy,Cell and Gene Therapy for Rare & Common Diseases,Tissue Science & Regenerative Medicine,Molecular Basis of Epigenetics,Bioengineering Therapeutics,Cell Science and Stem Cell Research,Clinical Trials on Cell & Gene Therapy,Nano Therapy,Genetic Engineering,Advanced Gene Therapeutics,Genetics & Genomic Medicine,Ethical Issues in Cell and Gene Therapy,Cell Therapy for Cardiovascular and Neurological Disorders,Regulatory and Safety Aspects of Cell and Gene Therapy,Markets & Future Prospects for Cell & Gene Therapy,Commercialization,