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Dictyostelium discoideum Protocols
Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal tr...
Selected Technical Publications
Each no. represents the results of the FDA research programs for half of the fiscal year.
Handbook of Media for Environmental Microbiology
The second edition of a bestseller, this book provides a comprehensive reference for the cultivation of bacteria, Archaea, and fungi from diverse environments, including extreme habitats. Expanded to include 2,000 media formulations, this book compiles the descriptions of media of relevance for the cultivation of microorganisms from soil, water, an
Pharmaceutical Bioassays
The definitive compendium of bioassay procedures and applications A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models. Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories. Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activit...
Biken's Journal
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Biken Journal
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The Rhizosphere and Plant Growth
Papers Presented at a Symposium held May 8--11, 1989, at the Beltsville Agricultural Research Center (BARC), Beltsville, Maryland, U.S.A.
