Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Computational Systems Biology
Cellular communication is mediated by extracellular stimuli that bind cellular receptors and activate intracellular signaling pathways. Principal biochemical reactions used for signal transduction are protein or lipid phosphorylation, proteolytic cleavage, protein degradation and complex formation mediated by protein-protein interactions. Within the nucleus, signaling pathways regulate transcription factor activity and gene expression. Cells differ in their competence to respond to extracellular stimuli. A deeper understanding of complex biological responses cannot be achieved by traditional approaches but requires the combination of experimental data with mathematical modeling. Following a ...
Computational Systems Biology
This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. - Logical information flow aids understanding of basic building blocks of life through disease phenotypes - Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns - Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation - Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.
Protein tyrosine phosphatase interacting protein 51 during migration in HaCat cells
Survival comes and goes with migration! This thesis shows the importance of the Protein Tyrosine Phosphatase Interacting Protein 51 in migrating cells. Migrating cells are essential for wound healing - alias survival - or, on the other hand, are taking a responsible part of a carcinogen progress during metastatic invasion - alias death. Therefore, it is utmost of interest to discover more in detail the involved proteins and the protein-protein-interactions.
Figurativity Across Domains, Modalities and Research Practices
The human ability to think non-literally has attracted the interest of various scholars for thousands of years. Over the centuries, they have defined and studied an extensive variety of tropes, such as metaphor, metonymy, synecdoche, allegory, and irony, in terms of their communicative effectiveness and stylistic aesthetics and basically interpreted these simply as figurative linguistic expressions and mere flourishes adding flavour to underlying non-figurative content. Today, figurativity is understood as constitutive of various processes of human comprehension of the world, human communicative interactions, and everyday human functioning. This volume constitutes a representative selection ...
Seldin and Giebisch's The Kidney
A classic nephrology reference for over 20 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you resea...
