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The Cellular Basis of Morphogenesis
This series was established to create comprehensive treatises on specialized topics in developmental biology. Such volumes are especially vital in develop mental biology, since it is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting-ground for the various practitioners of this science, facilitating an integration of heterogeneous infor mation on. specific topics. Each volume is intended to provide the conceptual basis for a comprehen sive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of devel opmental biology should understand the experimental background of the field and be able to place that body of information in context to ascertain where additional research would be fruitful. At that point, the creative process takes over, and new experiments are designed. This series is intended to be a vital link in that ongoing process of learning and discovery. If it facilitates schol arship, it will serve an important function.
Morphogenesis of Thyroid Follicles in Vitro
The thyroid gland first appears in the phylogenic scale in the Lamprey larva, Ammocoetes, at the time of metamorphosis (see review by Constantinescu, 1972). In higher Vertebrates the adult thyroid gland consists of vesicles i. e. thyroid follicles containing colloid and lined with a cubic or prismatic epithelium. Since the end of the 19th century, many authors have studied the morphoge nesis of the follicles during the embryonic and fetal development of the gland in Man and other species, principally Chick, Rat and Rabbit. The development of techniques for culturing organs of higher animals, in particular the thyroid by Carrel and Burrows (1910) and Champy (1914, 1915), allowed the study of the survival in vivo or in vitro of grafts or explants of thyroid gland obtained from adult or fetal animals. In addition to organotypic cultures, techniques for culturing cell suspensions obtained by enzymatic dissociation have recently been refined. Moreover, histological examination of pathological human glands and adult thyroids experimentally stimulated by thyrotropin hormone (TSH) has provided additional data for the understanding of thyroid follicle morphogenesis.
Cell and Molecular Biology of Artemia Development
The brine shrimp Artemia has become an important experimental system for studies of the developmental process. In recent years the shrimp has yielded considerable information on the pattern of development, bio chemistry, and gene structure and expression of crustaceans. This book is a compilation of research activity from twenty five of the most active re search laboratories working with brine shrimp in the above areas. It also represents the proceedings of a NATO Advanced Research Workshop held in Montreal, Canada, August 11-13, 1988. The book contains twenty nine full papers covering the major areas discussed at the workshop. In addition, one page abstracts representing seventeen poster pr...
Cell Biology of Extracellular Matrix
In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the sam...
Quantum Photonics: Pioneering Advances and Emerging Applications
This book brings together reviews by internationally renowed experts on quantum optics and photonics. It describes novel experiments at the limit of single photons, and presents advances in this emerging research area. It also includes reprints and historical descriptions of some of the first pioneering experiments at a single-photon level and nonlinear optics, performed before the inception of lasers and modern light detectors, often with the human eye serving as a single-photon detector. The book comprises 19 chapters, 10 of which describe modern quantum photonics results, including single-photon sources, direct measurement of the photon's spatial wave function, nonlinear interactions and non-classical light, nanophotonics for room-temperature single-photon sources, time-multiplexed methods for optical quantum information processing, the role of photon statistics in visual perception, light-by-light coherent control using metamaterials, nonlinear nanoplasmonics, nonlinear polarization optics, and ultrafast nonlinear optics in the mid-infrared.
Neurobiology and Clinical Aspects of the Outer Retina
This book deals with the cellular biology, biochemistry and physiology of photoreceptors and their interactions with the second-order neurons, bipolar and horizontal cells. The focus is upon the contributions made by these neurons to vision. Thus the basic neurobiology of the outer retina is related to the visual process, and visual defects that could arise from abnormalities in this part of the retina are highlighted in the first 16 chapters. Since all vertebrate retinas have the same basic structure and physiological plan, examples are given from a variety of species, with an emphasis upon mammals, extending to human vision. The last four chapters approach the problem from the other end. T...
Neuronal Operations in the Visual Cortex
The invitation by the editors of the series "studies of brain function" to contribute a monograph on the visual cortex gives me the opportunity to present in a concentrated manner much of the work I have done on the visual cortical areas of cat and monkey. However, the field of visual cortical physi ology is so active and so diverse that the presentation of only my own work would have given a very incomplete view of visual cortical functioning. Therefore this monograph also reviews most of the studies carried out on the subject in the last two decades. Where possible I have tried not only to describe the cortical machinery but also its possible functional purpose regarding vision. In doing t...
Annual Report
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Hierarchical Genome And Differentiation Waves, The: Novel Unification Of Development, Genetics And Evolution (In 2 Volumes)
Over the past few decades numerous scientists have called for a unification of the fields of embryo development, genetics, and evolution. Each field has glaring holes in its ability to explain the fundamental phenomena of life. In this book, the author shows how the phenomenon of cell differentiation, considered in its temporal and spatial aspects during embryogenesis, provides a starting point for a unified theory of multicellular organisms (plants, fungi and animals), including their evolution and genetics. This unification is based on the recent discovery of differentiation waves by the author and his colleagues, described in the appendices, and illustrated by a flip movie prepared by a medical artist. To help the reader through the many fields covered, a glossary is included.This book will be of great value to the researcher and practicing doctors/scientists alike. The research students will receive an in-depth tutorial on the topics covered. The seasoned researcher will appreciate the applications and the gold mine of other possibilities for novel research topics.
