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Targeted Therapy for the Central Nervous System: Formulation, Clinical Challenges, and Regulatory Strategies presents research on various delivery methods of drugs to the central nervous system and brain. This volume examines targeted therapies for neurodegenerative disorders and succinctly outlines the future of drug delivery systems, highlighting significant advancements specifically relating to central nervous system delivery. This book will be of great interest to researchers working in the field of neuroscience and pharmacology as well as clinicians (pharmacists, radiologists, psychiatrists). - Provides a current, thorough means on how drugs are delivered to the neurological system - Figures a connection amongst the physiology of drug delivery pertaining to the central nervous system, fundamentals of drug delivery, and distribution principles - Gives an accounting of clinical trials and regulatory approaches for the formulations targeting brain
Das Nachschlagewerk für die tägliche Arbeit in Klinik und Praxis! Aus den Rezensionen zur 1. Auflage: "Dieses Nachschlagewerk für die tägliche Arbeit in Klinik und Praxis ist ohne Einschränkung zu empfehlen." [Die Medizinische Welt, September 2003] "Gelingt es dem Herausgeber- und Autorenteam, in Zukunft diese hohe Qualität und Aktualität beizubehalten, so wird dieses Werk mit Sicherheit zum deutschsprachigen Standard-Therapie-Handbuch der Inneren Medizin." [Prof. Dr. K.-J. Paquet, Bad Kissingen] "Ein Zugewinn für Ärzte und alle anderen, die sich schnell und umfassend über die aktuellen, evidenzbasierten Therapieempfehlungen informieren möchten [..] mit dem Werk (wird) ein neuer W...
Die gesamte internistische Therapie mit einem Griff! Erfahrene Autoren aus Deutschland, Österreich und der Schweiz behandeln kompakt und umfassend alle internistischen Fachgebiete mit den Nachbarfächern Pädiatrie, Psychiatrie, Dermatologie, Intensiv- und Notfallmedizin. Praxisgerecht für den täglichen Einsatz - Aktuelle Therapie-Empfehlungen mit ausführlicher Begründung - Übersichtliche Flussdiagramme, Tabellen und Abbildungen - Einheitliche Kapitelstruktur - Lesefreundlich, schnell überschaubar, zweifarbig Das neue Standardwerk der internistischen Therapie!
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The first complete biography of an influential historian whose dramatic life intersected with many great events and thinkers of the twentieth century This is the first complete biography of Ernst Kantorowicz (1895–1963), an influential German-American medieval historian whose colorful life intersected with many of the great events and thinkers of his time. Born into a wealthy Prussian-Jewish family, he fought in World War I—earning an Iron Cross and an Iron Crescent—before being sent home following an affair with a general’s mistress. Though he was an ardent German nationalist during the Weimar period, after the Nazis came to power he bravely spoke out against the regime before an ov...
Explores German engagement with the Italian Renaissance in the decades from German unification to the Weimar republic.
Recent advances in the understanding of the biological basis of pediatric soft-tissue and bone tumors, especially owing to the advent of “omics” technologies, have led to an exponential increase in the current knowledge on the genetic and cellular patho-mechanisms that drive these diseases. This offers the unprecedented opportunity to develop and implement targeted therapies such as monoclonal antibodies, small molecules, oncolytic viruses, and immunotherapies in standard and/or personalized treatment regimens. However, to date only a few examples document a successful translation of discoveries from the bench to the bedside. Recent international expert congresses further emphasize the u...