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Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are cove...
Diabetes mellitus is a metabolic disease characterized by chronic high blood glucose levels. Of the various types of diabetes, type 2 diabetes is increasing in prevalence due to obesity, aging, sedentarism, and other factors. This book presents a novel approach to preventing and treating type 2 diabetes. Chapters cover such topics as diagnosis, pathogenesis, management, lifestyle and nutritional intervention, and systems to support early diagnosis and prevention of prediabetes.
Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes should be evaluated for subjects with congenital hypothyroidism, which genetic tests should be ordered in obese patients or for those with parathyroid carcinoma, and the rationale behind testing for multiple endocrine neoplasias. - Offers a clear presentations of pharmacogenetics and the actual assays used in detecting endocrine diseases - Teaches the essentials of the genetic basis of disease in each major endocrine organ system - Offers expert advice from genetic counselors on how to use genetic information in counseling patients - Includes new chapters on the genetics of lipid disorders and glycogen storage diseases, genetics of hypoglycemia, and whole genome/exome sequencing
With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients' quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implant...
Practical Pediatric Endocrinology in a Limited Resource Setting provides a guide for managing pediatric endocrine problems in a limited resource setting, together with an outline of the bases for these disorders. The book outlines a plan for coming to a likely diagnosis in situations where resources are constrained, and suggests ways to access more sophisticated technologies for diagnostic confirmation and extension of available tools. Further extending and complementing each chapter is a series of scenarios for use as teaching and learning tools. Together with a clinical question, all chapters include a suggested outline for assessment that assists readers facing similar situations in daily...
This book provides a comprehensive and self-contained introduction to federated learning, ranging from the basic knowledge and theories to various key applications. Privacy and incentive issues are the focus of this book. It is timely as federated learning is becoming popular after the release of the General Data Protection Regulation (GDPR). Since federated learning aims to enable a machine model to be collaboratively trained without each party exposing private data to others. This setting adheres to regulatory requirements of data privacy protection such as GDPR. This book contains three main parts. Firstly, it introduces different privacy-preserving methods for protecting a federated lear...
Since the dissolution of the Soviet Union almost a decade ago, there has been rapid evolution of interactions between the Western nations and individual countries of the former Soviet Union. As part of that interaction, the autonomous independent Republic of Azerbaijan through its scientific arm, the Geological Institute of the Azerbaijan Academy of Sciences under the Directorship of Academician Akif Ali-Zadeh and Deputy Director Ibrahim Guliev, arranged for personnel to be seconded to the University of South Carolina. The idea here was to see to what extent a quantitative understanding could be achieved of the evolution of the Azerbaijan part of the South Caspian Basin from dynamical, therm...
Intended for diabetes researchers and medical professionals who work closely with patients with diabetes, this newly updated and expanded edition provides new perspectives and direct insight into the causes and consequences of this serious medical condition from one of the foremost experts in the field. Using the latest scientific and medical developments and trends, readers will learn how to identify, prevent, and treat this challenging phenomenon within the parameters of the diabetes care regimen.
The incidence of diabetes is increasing at epidemic proportions worldwide, presenting a huge challenge to modern medicine. In response, scientific advances in the understanding of diabetes and its complications are being translated into improved clinical practice at ever faster rates. Greater understanding of aetiopathogenesis of the different types of diabetes, the emerging roles of novel pharmacological agents and the importance placed on multidisciplinary team working and multi-risk-factor treatment all contribute to this. Now in a fully revised second edition, this clear, concise guide to modern diabetes and its management will prove invaluable to all health professionals in this field. ...