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Improving Responses to Immunotherapy in Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is a uniformly fatal primary brain tumour. Whilst many therapeutic interventions have been studied pre-clinically very few new therapies have been approved for the use of GBM therapy. These tumours present a unique challenge due to their location within the brain, making delivery of therapeutic interventions challenging. Active immunotherapy represents an attractive avenue for therapy, with activated immune cells being shown to cross the blood brain barrier and penetrate brain tumours. Despite several advances being made in numerous other cancer types, many immunotherapeutic interventions in GBM have failed to make it past phase 3 clinical trials and as of now (2022) no immunotherapeutic interventions have been approved for the therapy of GBM.
Prostate Cancer Methods and Protocols
Prostate cancer is the second leading cancer in men in Western society. A major concern, and an area of intensive research, involves understanding why certain prostate cancers remain localized or indolent, whereas others become aggressive and metastasize. The differences between these cancer types have profound implications for patients and physicians. Indolent d- ease, which grows very slowly, generally does not cause any problems to the patient, whereas aggressive disease requires immediate treatment, the earlier the better. At present, there are no markers that discriminate between these two entities, thus causing a dilemma for the management of patients who have recently been diagnosed. ...
Tumor Immunology and Immunotherapy
Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
Advanced Practice in Endocrinology Nursing
This book provides a comprehensive guide for nurses practicing in any area of endocrinology and at any level of expertise. Endocrinology Nursing is a fast-developing specialty with nurses performing advanced roles and expanding their practice to run independent nurse-led services. Supported by the European Society of Endocrinology (ESE) and edited by members of the ESE Nurses Working Group, this is the first book ever published specifically for endocrine nurses. It is also an excellent resource for endocrinology specialty trainees, general practitioners, medical and nursing students, expert patients and nurses working in specialties such as fertility, osteoporosis, oncology, obesity, urology...
Cancer Research
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From the War on Poverty to the War on Crime
Co-Winner of the Thomas J. Wilson Memorial Prize A New York Times Notable Book of the Year A New York Times Book Review Editors’ Choice A Wall Street Journal Favorite Book of the Year A Choice Outstanding Academic Title of the Year A Publishers Weekly Favorite Book of the Year In the United States today, one in every thirty-one adults is under some form of penal control, including one in eleven African American men. How did the “land of the free” become the home of the world’s largest prison system? Challenging the belief that America’s prison problem originated with the Reagan administration’s War on Drugs, Elizabeth Hinton traces the rise of mass incarceration to an ironic sour...
