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The Bipolar Brain
"Although efforts to examine the structure and function of the human brain stretch back centuries (Paluzzi et al, 2007), techniques allowing the study of living humans are a relatively recent development. Early investigators confined themselves to largely studying external features, with 18th century methodologies such as phrenology purporting to link extracranial proxies for brain size and structure to specific personality traits (Livianos-Aldana et al, 2007). However, these techniques did not prove useful for either clinical or research purposes. Two-dimensional x-ray imaging, while constituting an important medical advance, did not provide sufficient soft tissue contrast to be useful for studying "functional" psychiatric disorders such as bipolar disorder; techniques to enhance contrast, such as ventriculography and pneumoencephalography were similarly limited (Figure 1.1). Wide-spread in vivo studies of brain morphometry had to await the development of computed tomography imaging (CT) in the early 1970s. By the early 1980s CT was already being applied to the study of bipolar disorder (Pearlson et al, 1981)"--
Bipolar Disorder
"Bipolar disorders are among the more common conditions affecting humankind and are, consequently, leading causes of disability worldwide. These illnesses are dynamic and complex, so that identifying them and then provide optimal management can be challenging. Because of this complexity, these conditions often comprise a disproportionate amount of most psychiatric practices, as specialty care that exceeds what can be delivered by other practitioners is often required. With these challenges in mind, we created this book to provide a comprehensive, readable review of these illnesses with chapters written by international experts in bipolar disorder"--
Bipolar Disorder in Youth
'Bipolar Disorder in Youth' provides a timely, focused review of the diagnosis, treatment, and neurobiology of bipolar disorder in youth. The editors and authors of each chapter represent international leaders in the care and study of this population. This book is the most comprehensive volume available discussing this important population and is a 'must' for the libraries of clinicians and scientists working with bipolar children and adolescents.
The American Psychiatric Association Publishing Textbook of Mood Disorders, Second Edition
Preceded by: The American Psychiatric Publishing textbook of mood disorders / edited by Dan J. Stein, David J. Kupfer, Alan F. Schatzberg. 1st ed. c2006.
The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterized by the complexity of causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunities to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances int...
Depression
This book provides an introduction to depression, including common comorbid conditions and differential diagnoses, treatment strategies, and considerations in special populations.
Pharmacotherapy for Mood, Anxiety, and Cognitive Disorders
Our limited knowledge of the pathophysiology underlying mood disorders contrasts sharply with the efficacy of the treatment modalities developed over the past decades. There has been an explosion of new antidepressant and anxiolytic medications, as well as mood stabilizers and compounds that aim to improve cognition. Although treatment success is still not optimal, pharmacotherapy for mood disorders and cognitive disorders is effective and is improving. Pharmacotherapy for Mood, Anxiety, and Cognitive Disorders takes a critical look at the medications available for treating mood, anxiety and cognitive disorders; their relevance to pathobiology and underlying mechanisms; and their limitations...
Substance Use Disorders
"Over the last few years there has been an increased interest in identification and treatment of substance use disorders, due at least in part to the widespread drug overdose epidemic. Clinicians and the lay public have gained a greater understanding of the need for treatment of substance use disorders and the consequences of avoiding treatment. In addition, there has been a growing understanding of substance use disorders as medical or mental health disorders, rather than character flaws or merely illegal activities. This book builds on this nascent understanding and presents epidemiology, basic science, and treatment from the perspective of a clinician who wants to gain knowledge and backg...
Personality Disorders
"Personality is not about what disorders you have but about who you are. It refers to a person's characteristic patterns of thought, feeling, behavior, motivation, defense, interpersonal functioning, and ways of experiencing self and others. All people have personalities and personality styles. While there are as many personalities as people, clinical knowledge accrued over generations has given rise to a taxonomy of familiar personality styles or types. Most people, whether healthy or troubled, fit somewhere in the taxonomy. Empirical research over the past two decades has confirmed the major personality types and their core features.1-5 Most clinical theorists do not view the personality t...
Emergency Psychiatry
Psychiatric emergencies are encountered throughout the practice of medicine, in many clinical settings. They may range from a patient expressing suicidal thoughts in an outpatient medical visit to an agitated, threatening patient with psychosis who is acutely intoxicated brought to the Emergency Department by ambulance. Decisions regarding admission, discharge, treatment, and referral are time-sensitive in the emergency setting or when acute safety issues are at stake. A broad knowledge of psychiatry and an understanding of potential medical etiologies of behavioral changes are important, as well as skills navigating what can be a complicated consultation relationship with the emergency depa...
