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Neuroimmune Interface in Health and Diseases
It is now well appreciated that the immune system, in addition to its traditional role in defending the organism against pathogens, communicate in a well-organized fashion with the brain to maintain homeostasis and regulate a set of neural functions. Perturbation in this brain-immune interactions due to inflammatory responses may lead to psychiatric and neurological disorders. Microglia are one of the essential cells involved in the brain-immune interactions. Microglial cells are now not simply regarded as resident tissue macrophages in the brain. These cells are derived from myeloid progenitor cells in the yolk sac in early gestation, travel to the brain parenchyma and interact actively wit...
CIO
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City Cycling
A guide to today's urban cycling renaissance, with information on cycling's health benefits, safety, bikes and bike equipment, bike lanes, bike sharing, and other topics. Bicycling in cities is booming, for many reasons: health and environmental benefits, time and cost savings, more and better bike lanes and paths, innovative bike sharing programs, and the sheer fun of riding. City Cycling offers a guide to this urban cycling renaissance, with the goal of promoting cycling as sustainable urban transportation available to everyone. It reports on cycling trends and policies in cities in North America, Europe, and Australia, and offers information on such topics as cycling safety, cycling infra...
Opening the East River
After the Civil War, the New York City's East River was a massive unsolved and dangerous navigation problem. A major waterway into and out of the Harbor--where customs revenue equaled 42 percent of the U.S. Government's income--the river's many hindrances, centered around Hell Gate, included whirlpools, rocks and reefs. These, combined with swirling currents and powerful tides, led to deaths, cargo losses and destruction of vessels. Charged with clearing the river, General John Newton of the Army Corps of Engineers went to work with the most rudimentary tools for diving, mining, lighting, pumping and drilling. His crews worked for 20 years, using a steam-drilling scow of his own design and a new and perilous explosive--nitroglycerine. In 1885, Newton destroyed the nine-acre Flood Rock with 282,730 pounds of high explosives. The demolition was watched by tens of thousands. This book chronicles the clearing of the East River and the ingenuity of the Army engineer whose work was praised by the National Academy of Sciences.
On RACE and RACISM: Humanity's Bottom Line
Lauren Joichin Nile introduces what she believes is humanity’s racial bottom line with a compelling account of her personal experiences growing up in 1950’s and 60’s segregated New Orleans. In so doing, she posits what she believes is humanity’s universal racial story. Lauren explains how starting out from Southern Africa, fully formed human beings, over thousands of years, walked out of Africa, populated the entire rest of Planet Earth, and over 2,000 generations, physically adapted to their new environments, gradually taking on the appearance of the many races of modern-day humanity, making all of us literally one, biologically-related human family. She then provides an abbreviated...
Proceedings RMRS.
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Handbook of Materials for Nanomedicine
In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of lipid-based and inorganic nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. The materials discussed include liposome-scaffold systems, elastic liposomes, targeted liposomes, solid lipid nanoparticles, lipoproteins, exosomes, porous inorganic nanomaterials, silica nanoparticles, and inorganic nanohybrids. The book provides all available information about them and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully.
