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This much anticipated Third Edition provides a comprehensive presentation of the global burden and patterns of cancer occurrence, along with new developments in our understanding of cancer causation and prevention. Special attention is given to epidemiologic approaches that incorporate molecular biomarkers based on genomic and other emerging technologies, providing new insights into the role of genetic predisposition and gene-environment interactions in cancer induction. In addition, new chapters are included on social class disparities in cancer incidence and mortality, the role of obesity and physical inactivity in cancer etiology, the potential effects of electromagnetic fields and rediofrequency radiation, and the principles of cancer chemoprevention. The textbook is organized into five sections: Basic Concepts; The Magnitude of Cancer; The Causes of Cancer; Cancer by Tissue of Origin; Cancer Prevention and Control. In this new edition, Drs. David Schottenfeld and Joseph F. Fraumeni, Jr. have enlisted three distinguished Associate Editors: Drs. Jonathan Samet of Johns Hopkins University, Graham Colditz of Harvard University and Alice Whittemore of Stanford University.
Vitamin A (retinol) is an essential dietary compound with myriad metabolic and regulatory functions. Deficiency can result in vision problems, compromised immune responses, and a host of other medical issues. More than 600 carotenoids have been identified in plants, algae, fungi, and bacteria, and around 50 carotenoids-includingcarotene-can be co
This ground-breaking clinical reference provides a comprehensive perspective of the multiple issues facing cancer survivors, ranging from early post-treatment through long-term care. Clear, clinically practical chapters written by experts in the field concentrate on multi-dimensional issues that confront cancer survivors. Divided into four, focused sections—overview of survivorship, medical care, psychosocial care, and epidemiologic—this book is evidence-based and uses case examples and illustrations throughout to add to the understanding of the material and its application to the individual patient. Primary care physicians, nurses, oncologists, hematologists, students of medicine, and survivorship researchers will all find this to be a valuable asset in setting the standard of care in the field of cancer survivorship.
The role of antioxidants and other nutritional agents in disease prevention is a widely discussed subject, attracting attention from professionals in all areas of medicine. This often-debated and rapidly evolving area of medicine could have important implications for how diseases are treated.
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.
Foundations and Applications of Statistics simultaneously emphasizes both the foundational and the computational aspects of modern statistics. Engaging and accessible, this book is useful to undergraduate students with a wide range of backgrounds and career goals. The exposition immediately begins with statistics, presenting concepts and results from probability along the way. Hypothesis testing is introduced very early, and the motivation for several probability distributions comes from p-value computations. Pruim develops the students' practical statistical reasoning through explicit examples and through numerical and graphical summaries of data that allow intuitive inferences before intro...
Section 141 of The Healthy, Hunger-Free Kids Act of 20101 provides funding for a research program on the causes and consequences of childhood hunger and food insecurity, and the characteristics of households with childhood hunger and food insecurity, with a particular focus on efforts to improve the knowledge base regarding contributing factors, geographic distribution, programmatic effectiveness, public health and medical costs, and consequences for child development, well-being, and educational attainment. The Economic Research Service and Food and Nutrition Service of the US Department of Agriculture conducted two outreach efforts to obtain input from the research community and other stak...
Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and high-calorie diets have been recognized as major risk factors for a variety of chronic diseases from cancer to metabolic diseases. All these risk factors are linked to ch
Named after Selene, Greek goddess of the moon, selenium (Se) has moved has moved from being thought of as a toxicant to being considered an essential nutrient with the potential to reduce cancer risk in the span of seven decades. Diversity of Selenium Functions in Health and Disease focuses on current knowledge of aspects of Se research relevant to