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Human Retrovirus Protocols
A cutting-edge collection of basic and state-of-the-art methods optimized for investigating the molecular biology of this class of retrovirus. These readily reproducible techniques range from methods for the isolation and detection of human retroviruses to cutting-edge methods for exploring the interplay between the viruses and the host. Here, the researcher will find up-to-date techniques for the isolation and propagation of HIV, HTLV, and foamy virus from a variety of sources. There are also assays for determining the cell tropism of HIV-1, the coreceptor usage of HIV-1, and human gene expression with HIV-1 infection by microarrays, as well as for phenotyping HIV-1 infected monocytes and examining their fitness. Highlights include the detection and quantification of HIV-1 in resting CD4+, a new cloning system for making recombinent virus, cDNA microarrays, and the determination of genetic polymorphisms in two recently identified HIV-1 co-factors that are critical for HIV-1 infection.
Active Ageing and Labour Market Engagement
The book provides an interesting analysis of the time-use data to examine the extent to which active ageing is occurring in India. It also synthesizes data from the National Sample Survey Office All India Survey and another survey undertaken in Kolkata, Bhubaneswar, and Ranchi (capital cities of East Indian states) to examine the role of the aged in the Indian Society. Nearly all countries in the world are experiencing an important issue of ageing. India faces its own set of challenges with its aging population due to the absence of a social security system—the shifting family dynamics questions the contribution of the elderly to the family in every aspect. Econometric models have been used in the book to study gender differences and variations across socio-economic conditions, correlating them to the contribution of the aged to their families and the extent of active ageing. The book broadens the understanding on the aged and facilitates their integration in the society so that they can age more actively. Active Ageing and Labour Market Engagement offers an analytical perspective to professionals, researchers, and policy makers interested in gerontology.
Sande's HIV/AIDS Medicine
Access the latest information available in the challenging area of HIV/AIDS management with Sande's HIV/AIDS Medicine, 2nd Edition. Authored by a veritable "who's who" of current global experts in the field, this medical reference book will provide you with all the practical, indispensable guidance you'll need to offer your patients the best possible care. Access reliable, up-to-the-minute guidance that addresses the realities of HIV/AIDS management in your geographical region, thanks to contributions from a global cast of renowned expert clinicians and researchers. Locate the clinically actionable information you need quickly with an organization that mirrors the current state of the AIDS e...
Emerging Infections 9
Based on the recent Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America sessions. • Focuses on a broad range of infectious agents that pose challenges for the clinical, laboratory, research, public health, and animal health communities. • Reflects the diversity of infectious agent threats in the 21st century. Some of these agents have been only recently discovered, such as the Acanthamoeba polyphaga mimivirus. Others are known pathogens presenting new challenges, such as human adenovirus 14.
Abstracts 1001-3102
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T Cell Regulation by the Environment
Naïve T cells get activated upon encounter with their cognate antigen and differentiate into a specific subset of effector cells. These T cells are themselves plastic and are able to re-differentiate into another subset, changing both phenotype and function. Differentiation into a specific subset depends on the nature of the antigen and of the environmental milieu. Notably, certain nutrients, such as vitamins A and D, sodium chloride, have been shown to modulate T cell responses and influence T cell differentiation. Parasite infection can also skew Th differentiation. Similarly, the gut microbiota regulates the development of immune responses. Lastly, the key role of metabolism on T cells has also been demonstrated. This series of articles highlights some of the multiple links existing between environmental factors and T cell responses.
The HIV Pandemic
As we approach the 25th anniversary of the first recognition of HIV/AIDS in 1981, this book reflects on the international impact of the disease. It has persistently remained a global issue, with more than 50 million people worldwide estimated to have been infected since that date. This ambitious book, written by 165 authors from 30 countries, offers a multi-country comparative study that examines how the response to the common, global threat of HIV is shaped by the history, culture, institutions and health systems of the individual countries affected. Increasingly the shift of health systems has been from prevention only as the main containment strategy, to a strategy that includes scaling u...
Logan Turner's Diseases of the Nose, Throat and Ear, 10Ed
'I am unaware of any textbook which provides such comprehensive coverage of the field and doubt that this work will be surpassed in the foreseeable future, if ever!' From the foreword by Robert C. Moellering, Jr., M.D, Shields Warren-Mallinckrodt Professor of Medical Research, Harvard Medical School, USA Kucers' The Use of Antibiotics is the leading major reference work in this vast and rapidly developing field. More than doubled in length compared to the fifth edition, the sixth edition comprises 3000 pages over 2-volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided ...
