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Selected Works of Terry Speed
The purpose of this volume is to provide an overview of Terry Speed’s contributions to statistics and beyond. Each of the fifteen chapters concerns a particular area of research and consists of a commentary by a subject-matter expert and selection of representative papers. The chapters, organized more or less chronologically in terms of Terry’s career, encompass a wide variety of mathematical and statistical domains, along with their application to biology and medicine. Accordingly, earlier chapters tend to be more theoretical, covering some algebra and probability theory, while later chapters concern more recent work in genetics and genomics. The chapters also span continents and generations, as they present research done over four decades, while crisscrossing the globe. The commentaries provide insight into Terry’s contributions to a particular area of research, by summarizing his work and describing its historical and scientific context, motivation, and impact. In addition to shedding light on Terry’s scientific achievements, the commentaries reveal endearing aspects of his personality, such as his intellectual curiosity, energy, humor, and generosity.
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The Twyning
In a harsh and dangerous world, a rat and a boy must each choose their way as their fates become inextricably linked. Efren is a young rat, unnoticed and timid among the kingdom of rats living in the London sewers. When the king dies, leaving the kingdom in upheaval, only Efren dares to journey into the human world, where he discovers a human doctor’s plan to destroy London’s entire rat population. Meanwhile, Peter, otherwise known as Dogboy, does odd jobs for both the scheming doctor and the town ratcatcher. But his gift for understanding animals — even rats — forces him to decide where his allegiances truly lie. Dogboy and Efren, along with the waifish girl Caz and her pet rat, Malaika, set out to test the strengths of friendship and loyalty against the gut-wrenching cruelties of the world.
Statistical Analysis of Next Generation Sequencing Data
Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that surrounds us today. To extract signals from high-dimensional NGS data and make valid statistical inferences and predictions, novel data analytic and statistical techniques are needed. This book contains 20 chapters written by prominent statisticians working with NGS data. The topics range from basic preprocessing and analysis with NGS data to more complex genomic applications such as copy number variation and isoform expression detection. Research statisticians who want to learn about this grow...
Total Immersion
Swim better—and enjoy every lap—with Total Immersion, a guide to improving your swimming from an expert with more than thirty years of experience in the water. Terry Laughlin, the world’s #1 authority on swimming success, has made his unique approach even easier for anyone to master. Whether you’re an accomplished swimmer or have always found swimming to be a struggle, Total Immersion will show you that it’s mindful fluid movement—not athletic ability—that will turn you into an efficient swimmer. This new edition of the bestselling Total Immersion features: -A thoughtfully choreographed series of skill drills—practiced in the mindful spirit of yoga—that can help anyone swim more enjoyably -A holistic approach to becoming one with the water and to developing a swimming style that’s always comfortable -Simple but thorough guidance on how to improve fitness and form -A complementary land-and-water program for achieving a strong and supple body at any age Based on more than thirty years of teaching, coaching, and research, Total Immersion has dramatically improved the physical and mental experience of swimming for thousands of people of all ages and abilities.
Principles of Analog Electronics
In the real world, most signals are analog, spanning continuously varying values. Circuits that interface with the physical environment need to be able to process these signals. Principles of Analog Electronics introduces the fascinating world of analog electronics, where fields, circuits, signals and systems, and semiconductors meet. Drawing on the author’s teaching experience, this richly illustrated, full-color textbook expertly blends theory with practical examples to give a clear understanding of how real electronic circuits work. Build from the Essentials of Math, Physics, and Chemistry to Electronic Components, Circuits, and Applications Building a solid foundation, the book first e...
Expansion in Finite Simple Groups of Lie Type
Expander graphs are an important tool in theoretical computer science, geometric group theory, probability, and number theory. Furthermore, the techniques used to rigorously establish the expansion property of a graph draw from such diverse areas of mathematics as representation theory, algebraic geometry, and arithmetic combinatorics. This text focuses on the latter topic in the important case of Cayley graphs on finite groups of Lie type, developing tools such as Kazhdan's property (T), quasirandomness, product estimates, escape from subvarieties, and the Balog-Szemerédi-Gowers lemma. Applications to the affine sieve of Bourgain, Gamburd, and Sarnak are also given. The material is largely self-contained, with additional sections on the general theory of expanders, spectral theory, Lie theory, and the Lang-Weil bound, as well as numerous exercises and other optional material.
