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Clinical Relevance of the Immune-to-Brain and Brain-to-Immune Communications
Experimental and clinical evidence demonstrates an intense crosstalk among the nervous, endocrine and immune systems. The central nervous system (CNS) not only has the capacity to affect peripheral immune function, but is also able to sense and process signals from the peripheral immune system. The bi-directional interaction between the CNS and the peripheral immune system has gained great interest as it can help better understand disease pathophysiology as well as improving health and treatment outcomes in patients. On the one hand, inflammatory factors are known to affect CNS functions and to induce neuropsychiatric symptoms, making immune-to-brain communication highly relevant for psychiatric diseases and their treatments. On the other hand, analyzing pathways of brain-to-immune communication will help to understand the pathophysiology of chronic inflammatory disorders and will form the basis for optimizing treatment of these diseases.
Alzheimer's Disease and Infectious Causes
With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer's disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer's disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer's patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer's disease. Sources of infection in Alzheimer's disease vary from childhood infections t...
Central Nervous System Diseases and Inflammation
Edited and authored by top names in the field, this book provides a succinct reference on inflammatory central nervous system disease. It focuses on current areas of investigation in the fields of neuroimmunology, virology, pharmacology, and disease. Sections focus on specific categories of diseases, examining the pharmacological, virological, and immunological effects of and on the disease. This book’s unique organization provides a concise overview of inflammatory CNS disease.
Diseases of the Brain, Head and Neck, Spine 2020–2023
This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Current Advances in Anaerobic Digestion Technology
Anaerobic digestion (AD) is one of the oldest biotechnological processes and originally referred to biomass degradation under anoxic conditions in both natural and engineered systems. It has been used for decades to treat various waste streams and to produce methane-rich biogas as an important energy carrier, and it has become a major player in electrical power production. AD is a popular, mature technology, and our knowledge about the influencing process parameters as well as about the diverse microbial communities involved in the process has increased dramatically over the last few decades. To avoid competition with food and feed production, the AD feedstock spectrum has constantly been ex...
An Introduction to Powder Metallurgy
First published in 1994. Routledge is an imprint of Taylor & Francis, an informa company.
Functional Neuroradiology
Functional Neuroradiology: Principles and Clinical Applications, is a follow-up to Faro and Mohamed’s groundbreaking work, Functional (BOLD)MRI: Basic Principles and Clinical Applications. This new 49 chapter textbook is comprehensive and offers a complete introduction to the state-of-the-art functional imaging in Neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging. With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, Functional Neuroradiology is divid...
