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Millions of people worldwide are affected by neurological disorders which disrupt the connections within the brain and between brain and body causing impairments of primary functions and paralysis. Such a number is likely to increase in the next years and current assistive technology is yet limited. A possible response to such disabilities, offered by the neuroscience community, is given by Brain-Machine Interfaces (BMIs) and neuroprostheses. The latter field of research is highly multidisciplinary, since it involves very different and disperse scientific communities, making it fundamental to create connections and to join research efforts. Indeed, the design and development of neuroprosthet...
This book constitutes the refereed proceedings of the second International Conference on Biomimetic and Biohybrid Systems, Living Machines 2013, held in London, UK, in July/August 2013. The 65 revised full papers presented were carefully reviewed and selected from various submissions. The papers are targeted at the intersection of research on novel live-like technologies inspired by scientific investigation of biological systems, biomimetics, and research that seeks to interface biological and artificial systems to create biohybrid systems
Neuromorphic engineering has just reached its 25th year as a discipline. In the first two decades neuromorphic engineers focused on building models of sensors, such as silicon cochleas and retinas, and building blocks such as silicon neurons and synapses. These designs have honed our skills in implementing sensors and neural networks in VLSI using analog and mixed mode circuits. Over the last decade the address event representation has been used to interface devices and computers from different designers and even different groups. This facility has been essential for our ability to combine sensors, neural networks, and actuators into neuromorphic systems. More recently, several big projects ...
This book explains the application of recent advances in computational intelligence – algorithms, design methodologies, and synthesis techniques – to the design of integrated circuits and systems. It highlights new biasing and sizing approaches and optimization techniques and their application to the design of high-performance digital, VLSI, radio-frequency, and mixed-signal circuits and systems. This first of two related volumes addresses the design of analog and mixed-signal (AMS) and radio-frequency (RF) circuits, with 17 chapters grouped into parts on analog and mixed-signal applications, and radio-frequency design. It will be of interest to practitioners and researchers in computer science and electronics engineering engaged with the design of electronic circuits.
This book provides a comprehensive overview of the incredible advances achieved in the study of in vitro neuronal networks for use in basic and applied research. These cultures of dissociated neurons offer a perfect trade-off between complex experimental models and theoretical modeling approaches giving new opportunities for experimental design but also providing new challenges in data management and interpretation. Topics include culturing methodologies, neuroengineering techniques, stem cell derived neuronal networks, techniques for measuring network activity, and recent improvements in large-scale data analysis. The book ends with a series of case studies examining potential applications of these technologies.
Supported with over 280 illustrations and over 160 equations, the book offers cutting-edge guidance on designing integrated circuits for wireless biosensing, body implants, biosensing interfaces, and molecular biology. You discover innovative design techniques and novel materials to help you achieve higher levels circuit and system performance.
This book explains the application of recent advances in computational intelligence – algorithms, design methodologies, and synthesis techniques – to the design of integrated circuits and systems. It highlights new biasing and sizing approaches and optimization techniques and their application to the design of high-performance digital, VLSI, radio-frequency, and mixed-signal circuits and systems. This second of two related volumes addresses digital and network designs and applications, with 12 chapters grouped into parts on digital circuit design, network optimization, and applications. It will be of interest to practitioners and researchers in computer science and electronics engineering engaged with the design of electronic circuits.
Closed-loop neurophysiology has been accelerated by recent software and hardware developments and by the emergence of novel tools to control neuronal activity with spatial and temporal precision, in which stimuli are delivered in real time based on recordings or behavior. Real-time stimulation feedback enables a wide range of innovative studies of information processing and plasticity in neuronal networks. This Research Topic e-Book comprises 16 Original Research Articles, seven Methods Articles, and seven Reviews, Mini- Reviews, and Perspectives, all peer-reviewed and published in Frontiers in Neural Circuits. The contributions deal with closed loop neurophysiology experiments at a variety of levels of neural circuit complexity. Some include modeling and theoretical analyses. New enabling technologies and techniques are described. Novel work is presented from experiments in vitro, in vivo, and in humans, along with their clinical and technological implications for improving the human condition.
Numerical simulation is a technique of major importance in various technical and scientific fields. Whilst engineering curricula now include training courses dedicated to it, numerical simulation is still not well-known in some economic sectors, and even less so among the general public. Simulation involves the mathematical modeling of the real world, coupled with the computing power offered by modern technology. Designed to perform virtual experiments, digital simulation can be considered as an "art of prediction". Embellished with a rich iconography and based on the testimony of researchers and engineers, this book shines a light on this little-known art. It is the second of two volumes and gives examples of the uses of numerical simulation in various scientific and technical fields: agriculture, industry, Earth and universe sciences, meteorology and climate studies, energy, biomechanics and human and social sciences.
As rapid technological developments occur in electronics, photonics, mechanics, chemistry, and biology, the demand for portable, lightweight integrated microsystems is relentless. These devices are getting exponentially smaller, increasingly used in everything from video games, hearing aids, and pacemakers to more intricate biomedical engineering and military applications. Edited by Kris Iniewski, a revolutionary in the field of advanced semiconductor materials, Integrated Microsystems: Electronics, Photonics, and Biotechnology focuses on techniques for optimized design and fabrication of these intelligent miniaturized devices and systems. Composed of contributions from experts in academia a...